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Found 86 clinical trials
Pulse Oximetry in Healthy SubjEcts ImmergeD in OceaN.

Drowning is the 3rd leading cause of accidental death in the world. One of the tools used by lifeguards to help ER assess gravity, is pulse oximetry. Its measure is variable even in optimal condition and its accuracy can be altered by factors specific to the patient and by environmental …

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  • 19 Feb, 2024
Sex & Sleep in Athletes

High training loads can therefore have negative influences both on sleep but also on the risk of injury in athletes. Understanding and studying, in different sports, how sexual / masturbatory activity can influence sleep has primary importance for athletic and medical staff of athletes with the ultimate aim of preserving …

anxiety
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  • 19 Feb, 2024
Prognostic Factors to Regain Consciousness

The study aims to identify factors that predict the medium and long-term outcome of patients with disorders of consciousness (DOC) undergoing early neurological rehabilitation. In this prospective, observational study, 130 DOC patients are going to be included (36 months). At study entry, different routine data, disease severity and functional status …

neurological rehabilitation
coma
encephalopathy
traumatic brain injury
hypoxia
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  • 19 Feb, 2024
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis

One of the most important pathophysiologic hallmarks in sepsis is vascular endothelial injury that contributes to the severity and outcome of the syndrome. Effective treatments for endothelial cell injury in sepsis have been lacking to improve prognosis.

dysregulated host response
diabetes
cell injury
septicemia
organ failure
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  • 19 Feb, 2024
Exploring Pathogenesis and Treatment of Hypercalcemia Caused by Intramuscular Injection of Paraffinoil

The aim of the study is to characterize paraffin oil induced granulomatous disease. We will investigate pathogenesis and natural history of paraffin disease. Subsequently, through further translational studies, we intend to identify novel treatments to be tested in future randomized clinical trials.

granulomatous disease
treatment of hypercalcemia
hypercalcemia
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  • 19 Feb, 2024
A Neuropsychological Test Battery for the Assessment of Time Deficits

Time processing involves different abilities - i.e. estimating the duration of an event and moving in past and future time - and it is a fundamental ability in everyday life. For these reasons the assessment and the rehabilitation of time deficits in brain damaged patients is extremely important. The ability …

cognitive deficits
cognitive deficit
neuropsychological test
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  • 19 Feb, 2024
The COVID-19 Disease and CARdiac Events Study

An observational study of consecutive patients testing positive for COVID-19 who require admission to hospital to determine the degree of myocardial injury through biomarkers and echocardiography and the impact of this on cardiovascular outcomes. The COVID-19 disease and CARdiac Events study (COVICARE).

covid-19
SARS
x-rays
acute respiratory syndrome (sars)
myocardial injury
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  • 19 Feb, 2024
Highly Suppressive Treg in Delayed and Slow Graft Function After Kidney Transplantation

Delayed/slow graft function is the most common complication after kidney transplantation with an incidence over 20% and is the result of ischemia-reperfusion injury. The increased use of marginal kidney grafts to palliate the organ shortage is leading to a continued rise in the incidence of delayed/slow graft function.

kidney transplant
graft failure
ischemic reperfusion injury
ischemia-reperfusion injury
ischemia
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  • 19 Feb, 2024
ASHCOM Shoulder System and Its Related Instruments

The objectives of this study are to confirm safety, performance and clinical benefits of the ASHCOM Shoulder System and its related instruments by analysis of standard scoring systems, radiographs and adverse event records.

total shoulder replacement
deficiency
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  • 19 Feb, 2024
Cancer Therapy Effects on the Heart

However, current strategies for identifying patients who are at risk prior to the development of significant changes in heart function are limited. This study will focus on imaging markers of cardiac injury and dysfunction with the goal of developing improved diagnostic tests and treatment strategies.

childhood cancer
cardiotoxicity
heart failure
metastasis
pediatric
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  • 19 Feb, 2024