Found 158 clinical trials
SCS Stimulation Clamp to Assess Impact of Stimulation on Glucose Metabolism
In 1967 spinal cord stimulation (SCS) for the treatment of chronic neuropathic pain was established. Today various pain syndromes like the failed back surgery syndrome (FBSS), the complex regional pain syndrome (CRPS), ischemic pain or phantom limb pain are treated with SCS.
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- 19 Feb, 2024
- 1 location
Comparison of Epidural Combined and Dural Puncture Labor Epidural on Pain and Course of Vaginal Delivery
The three standard techniques used for labor analgesia, thus epidural, combined spinal-epidural and dural puncture epidural will be compared regarding their impact on pain intensity, analgesic and local anesthetic consumption and course of vaginal delivery in a prospective, randomised, double blind manner
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- 19 Feb, 2024
- 2 locations
Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis
Therefore, the present study aims to evaluate the effects of erector spinae plane block on pain severity and clinical outcomes in patients with ankylosing spondylitis whose disease activity is controlled under treatment but who continue to experience persistent back pain.
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- 23 Jun, 2026
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases
Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …
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- 19 Feb, 2024
- 1 location
Adductor Canal Block (ACB) Versus ACB /Saphenous Block in Patients Undergoing Anterior Cruciate Ligament Repair
Knee surgeries are associated with severe postoperative pain. Blocking the femoral nerve (or saphenous nerve) in the adductor canal is increasingly used for knee analgesia. It carries potential benefits that encourage anesthesiologists to do it.
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- 19 Feb, 2024
- 1 location
Study on the Ability of Virtual Reality Glasses in Anxiety and Pain Reduction in 50 Women Undergoing Amniocentesis or Feticide
Both amniocenteses and especially feticide are procedures that incorporate both anxiety and pain. As anxiety and pain can be reduced when using a distraction, The investigators speculate that the use of virtual reality glasses during these procedures will elevate both anxiety and pain.
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- 19 Feb, 2024
- 1 location
Liberal vs. Restricted Post-discharge Opioid Prescribing Following Midurethral Sling
The specific objective of this proposal is to evaluate pain and opioid use following a midurethral sling (MUS) under two different opioid prescribing schemes. The central hypothesis is that, in spite of the fact that opioids are often routinely prescribed by many surgeons following this procedure, most patients do not …
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- 19 Feb, 2024
- 1 location
Ketamine Analgesia in Third Molar Surgery
METHOD At the start of surgery, Ketamine or placebo will be given in a vein to evaluate if the acute pain decreases significantly. Inflammation is known to cause pain. By measuring different proteins in the blood, the investigators want to understand how inflammation links to the pain.
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- 19 Feb, 2024
- 1 location
An N-of-1 Trial of an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain for Cancer-related Difficulties
<p>Chronic pain is a commonly occurring complication of cancer but access to the first-line recommended treatment (pain-focused cognitive behavioral therapy - CBT) is limited outside of specialist pain clinics in Sweden, and these clinics do not routinely accept people with cancer-related pain.
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- 15 Jan, 2025
- 1 location
Multiomics After Headache Provocation of People Who Are Unable to Have Headache
Headaches are extremely common illnesses with a combined lifetime prevalence of 90-99% in Europe. Despite this high prevalence, there are persons who have never, in their whole life, encountered a headache. The aim of the study is to identify factors that protect against headache by studying multiomics in people who …
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- 19 Feb, 2024
- 1 location