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Found 1383 clinical trials
Cisplatin+Pembrolizumab+RT in Vulvar Cancer

This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma. This research study involves the following: Cisplatin (standard of care drug) Pembrolizumab (investigational drug) Radiation Therapy (standard of care intervention)

anticoagulant therapy
measurable disease
endocrine therapy
pembrolizumab
anticoagulants
  • 0 views
  • 19 Feb, 2024
  • 1 location
InterLeukin-7 (CYT107) to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection UK Cohort

Comparison of the effects of CYT107 vs Placebo administered IM at 10g/kg twice a week for two weeks on immune reconstitution of lymphopenic COVID-19 patients.

covid-19
intermittent positive pressure ventilation
invasive positive pressure ventilation
interleukins
interleukin-7
  • 0 views
  • 19 Feb, 2024
  • 1 location
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma

This trial is a multi-center, phase III, randomized (1:1) clinical trial. The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.

carcinoma
stereotactic body radiation therapy
hepatocellular carcinoma
recurrent hepatocellular carcinoma
radiofrequency ablation
  • 0 views
  • 19 Feb, 2024
  • 1 location
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

aortic valve replacement
fatigue
regurgitation
shortness of breath
  • 0 views
  • 19 Feb, 2024
  • 10 locations
18F-PSMA-1007 PET Imaging to Detect Primary Prostate Cancer

To study the added value of 18F-PSMA-1007 PET to mpMRI in the detection of local prostate cancer lesions.

multiparametric magnetic resonance imaging
positron emission tomography
pet/ct scan
digital rectal examination
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension

This study is designed to investigate whether sympathoinhibition with moxonidine could provide added metabolic benefit compared to the second line therapy in the current guidelines.

hypertension
amlodipine
body mass index
moxonidine
ace inhibitor
  • 0 views
  • 19 Feb, 2024
  • 1 location
COVID19-Convalescent Plasma for Treating Patients With Active Symptomatic COVID 19 Infection (FALP-COVID)

COVID-19 infection has spread worldwide causing several deaths in few months Convalescent Plasma from COVID 19 donors has shown huge activity in small series from Chinese patients and currently many centers from USA and the European Union are assessing its use looking to avoid mortality and prolonged hospitalizations COVID-19-related

renal failure
fraction of inspired oxygen (fio2)
interleukin-6
neutrophil count
interleukins
  • 0 views
  • 19 Feb, 2024
  • 1 location
Moxibustion Plus Cupping in Convalescent Patients With COVID-19

This trial is designed to evaluate the efficacy and safety of moxibustion plus cupping in the convalescence of COVID-19.

asthenia
covid-19
convalescence
cough
chest tightness
  • 0 views
  • 19 Feb, 2024
  • 1 location
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-na ve GBM Patients.

A multi-center, open-label, single-arm, phase I/II clinical study is designed to test the safety and immunogenicity of an investigational Dendritic and Glioma Cells Fusion vaccine given with IL-12 for treatment-nave patients after resection of glioblastoma.

glioblastoma multiforme
blood cell count
glioma
temozolomide
ejection fraction
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Use of Safety Behaviors in Exposure Therapy for Arachnophobia

This study examines the impact of safety behaviors (i.e., unnecessary protective actions) on outcomes of exposure therapy for spider phobia. Researchers will compare exposure therapy with (a) no safety behaviors, (b) safety behaviors faded toward the end of treatment, and (c) unfaded safety behaviors.

arachnophobia
exposure therapy
phobia
  • 0 views
  • 19 Feb, 2024
  • 1 location