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Found 1399 clinical trials
Optimizing the Treatment Strategy for Age-related Macular Degeneration

The purpose of this study is to compare two different treatment protocols for wet macular degeneration; the new protocol called "Observe and Plan" against the current standard protocol "Treat and Extend". Studies suggest that patients achieve equally good visual acuity with fewer controls and that they are more satisfied with …

treatment protocols
macular degeneration
age-related macular degeneration
  • 0 views
  • 19 Feb, 2024
  • 3 locations
The Efficacy and Safety of Different Doses of SY-004 in Patients With Type 2 Diabetes Mellitus

This is a multicenter, randomized, double-blind, placebo-controlled phase II clinical study in patients with type 2 diabetes mellitus (T2DM).

antidiabetic agent
blood glucose self-monitoring
antidiabetic agents
monitors blood glucose
fasting
  • 0 views
  • 19 Feb, 2024
  • 1 location
Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence

This study is aimed to investigate the role of long-term diet adherence on manifestations of gastroesophageal reflux disease

antisecretory agents
reflux
acidity
oesophageal ph
acid reflux / gastroesophageal reflux
  • 0 views
  • 19 Feb, 2024
  • 1 location
Liberal vs. Restricted Post-discharge Opioid Prescribing Following Midurethral Sling

The specific objective of this proposal is to evaluate pain and opioid use following a midurethral sling (MUS) under two different opioid prescribing schemes. The central hypothesis is that, in spite of the fact that opioids are often routinely prescribed by many surgeons following this procedure, most patients do not …

opioid
narcotic use
postoperative pain
analgesia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Mechanism of Action of Transcranial Magnetic Stimulation

This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.

depressive episode
depressive disorder
psychiatric therapy
depression
major depressive disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

pembrolizumab
advanced solid tumor
advanced malignant solid tumor
HER2
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Heart Transplantation Using Normothermic Regional Perfusion Donation After Circulatory Death

Normothermic regional perfusion (NRP) utilizes Extracorporeal Membrane Oxygenation (ECMO) or cardiopulmonary bypass to reperfuse the heart and other organs in situ after isolation and ligation of the cerebral vessels. In situ resuscitation of the heart has the added advantage of allowing full hemodynamic and echocardiographic assessment of the donor heart …

heart transplantation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Open Label Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With isSCC

This is an open label, dose escalation study to evaluate the safety and efficacy of intralesional injection of STP705 in adult patients with Cutaneous Squamous Cell Carcinoma in situ (isSCC, Bowen's disease). The purpose of this trial is to evaluate the safety, tolerability and efficacy of various doses of STP705 …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Targeted Fortification of Donor Breast Milk in Preterm Infants

This study is a randomized controlled trial comparing standard fortification of donor breast milk to targeted fortification of donor breast milk in preterm infants. The purpose of the study is to determine if there is a benefit to target fortifying donor breast milk in the preterm population. The investigators hypothesize …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Thoracic Interfascial Plane Block Versus Thoracic Paravertebral Block in Gynecomastia Surgery

The growing increase in the number of gynecomastia surgeries has resulted in an increased need for anesthetic techniques with improved pain reduction, safety, and fewer complications. The aim of this work is to compare the efficacy of ultrasound guided thoracic interfascial plane block and ultrasound guided thoracic paravertebral block for …

gynecomastia
local anesthetics
anesthesia
local anesthesia
  • 0 views
  • 19 Feb, 2024
  • 1 location