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Found 1061 clinical trials
Innovating Access to Novel Therapies Through Standardized Prospective Integration of Response Evaluations (IMPACT-INSPIRE) (IMPACT-INSPIRE)

This observational study aims to assess the outcomes in patients with advanced treatment refractory cancers with matched molecular/precision therapy as per their molecular profiling results after discussion at molecular tumour board.To standardize response assessment and data collection for patients that are receiving off-label or non-standard therapies based on MTB recommendations.

  • 0 views
  • 07 May, 2025
Attitude of Egyptian Population Toward COVID 19 in Ramadan

Egyptian citizens were encouraged to adopt personal protective measures, such as staying at home , increasing personal hygiene and wearing protective face masks. Ramadan is a holy month and a very special event for all the Muslims worldwide including the Egyptian Muslims . the Egyptians have many rituals and traditions …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Immune Profiling of COVID19-patients Admitted to ICU

Throughout their ICU stay, multiple blood samples will be screened for leukocytes surface markers, leukocytes' production of certain molecules, and circulating cytokines/chemokines/checkpoint inhibitors. Their plasma/serum will be used as well for immune proteomics, metabolomics, and other serological tests. Such parameters can provide the more comprehensive status of COVID19-infected patients at …

SARS
covid-19
cytokines
acute respiratory syndrome (sars)
corticosteroids
  • 0 views
  • 19 Feb, 2024
  • 1 location
Non Inferiority Trial for Detection of nCOVID-19 Through Analysis of Exhaled Breath Aerosols

The clinical diagnosis of the subject based on a combination of imaging, viral diagnostics and clinical assessment will be used as the reference standard. When this number hits 100 the study will be discontinued. In total no more than 500 subjects shall be sampled in this trial.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Covid-19 Lockdown and Deviant Sexual Fantasies

The very characteristics of this confinement and of the disease (isolation, potential severity of the illness, being psychologically unprepared for such a circumstance) have a significant impact on one's psyche, like emotional disorders -anxiety/depression-, difficulties when returning to normal life, vicarious traumas Confinement is paradoxical in as although well-intended to …

  • 0 views
  • 19 Feb, 2024
  • 1 location
GFAP Auto-immunity : a French Cohort Study

Glial fibrillary acidic protein (GFAP)-Immunoglobulin G (IgG) have recently been described as a biomarker of a novel inflammatory central nervous system (CNS) disorder, termed autoimmune GFAP astrocytopathy. Thus far, four major clinical series have been published (two from Mayo Clinic USA, one from Italy and one from China).

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  • 19 Feb, 2024
  • 1 location
Development of a Simple Fast and Portable Recombinase Aided Amplification Assay for 2019-nCoV

In parallel, The investigators also used the commercial RT-qPCR assay kit for 2019-nCoV as a reference.

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  • 19 Feb, 2024
  • 1 location
Thyroid Disease Diagnosis by Mutiple Ultrasonic Factors.

The evaluation of the tumor microcirculation by Doppler ultrasound has been used in many tumors and defined as vascularity index (VI). The power Doppler sonography has many advantages over color Doppler ultrasound in studying the vascularity.

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  • 19 Feb, 2024
  • 1 location
Biomarkers in Rheumatoid Arthritis Treated With Anti-interleukin-6 Therapy

Indeed, usual inflammatory biomarkers used during the follow-up of these patients to detect persistent disease activity or intercurrent infection, such as C-reactive protein, fibrinogen and procalcitonin, are dependant on IL-6. Thse usual biomarkers cannot therefore be reliably used during anti-IL-6 therapy.

aspirin
tocilizumab
rheumatism
immunosuppressive agents
interleukin
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

A sterile cotton swab may be rubbed over their skin or inside the cheek or nose to collect cells. If participants have samples collected as part of their regular medical care, their doctor may be asked to send parts of the samples that otherwise would be thrown away. These samples …

autoimmune disease
episodic fever
endoscopies
gastrointestinal symptoms
dermatitis
  • 0 views
  • 19 Feb, 2024
  • 1 location