Found 730 clinical trials
Study of ATI-2138 in Adult Participants with Moderate to Severe Atopic Dermatitis
This is a Phase 2 open label study of ATI-2138 in participants with moderate to severe atopic dermatitis.
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- 23 Jan, 2025
- 5 locations
A Study to Evaluate Safety Tolerability Pharmacokinetics and Pharmacodynamics of UCB8600 in Healthy Participants Atopic Participants and Chronic Spontaneous Urticaria Participants
The purpose of the study is to assess safety, tolerability and pharmacokinetics (PK) of oral UCB8600.
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- 19 Feb, 2024
- 1 location
Tofacitinib for Immune Skin Conditions in Down Syndrome
People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions. The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug …
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- 19 Feb, 2024
- 1 location
Observational Evaluation of Atopic Dermatitis in Pediatric Patients (PEDISTAD)
Primary Objectives:To describe the characteristics of pediatric patients with moderate to severe atopic dermatitis (AD) whose disease is not adequately controlled with topical therapies or when those therapies are not medically advisable.
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- 23 May, 2025
- 1 location
Prospective Longitudinal Observational Research in Atopic Dermatitis
In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within a few years. This sequence is called atopic march. Atopic dermatitis and associated atopic diseases are more frequent in families, suggesting a genetic predisposition.
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- 24 Nov, 2025
- 1 location
Observational Evaluation of Atopic Dermatitis in Pediatric Patients
Primary Objectives: To describe the characteristics of pediatric patients with moderate to severe atopic dermatitis (AD) whose disease is not adequately controlled with topical therapies or when those therapies are not medically advisable.
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- 19 Feb, 2024
- 18 locations
Observational Study of Adult Patients Receiving Dupixent for Atopic Dermatitis (AD)
Primary Objective: To characterize the patients who receive Dupixent (dupilumab) for AD in a real-world setting, with respect to their medical history, socio-demographic and disease characteristics, and prior and concomitant treatments of AD Secondary Objectives: To characterize real-world use patterns of Dupixent for AD (eg, used regimens, reason for initiation …
- 0 views
- 19 Feb, 2024
- 20 locations
Evaluation of Biomarkers of Atopic Dermatitis in Pediatric Patients (PEDISTAD BIOMARKER STUDY)
Primary Objective: To explore associations between biomarkers of atopic dermatitis (AD) and: Disease state and time course of AD, Disease state and evolution of selected atopic comorbid conditions, Effectiveness of specific AD treatments.
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- 19 Feb, 2024
- 9 locations
The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis (DERMIND-AD)
This study aims to assess the impact of dupilumab on the mental health and quality of life of moderate-to-severe Atopic Dermatitis (AD) patients. The study will recruit participants from AD patients who are already receiving dupilumab treatment. The study enrollment period will be about 9 months with each of the …
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- 06 May, 2026
A Pilot Study to Explore the Role of Gut Flora in Eczema
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding eczema.
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- 19 Feb, 2024
- 1 location