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Found 992 clinical trials
Predicting Response of Metastatic Triple Negative Breast Cancer to Immunotherapy Based on Patients Cytokine Profile

Recent progress in immunotherapy (IT) has shifted treatment paradigms for multiple malignancies including breast cancer. It has been shown that levels of certain cytokines were correlated with increased response to immunotherapy in patients with metastatic breast cancer. In this study investigators will perform cytokine profiling among patients diagnosed with metastatic …

metastatic breast cancer
triple-negative breast cancer
multiple malignancies
cancer
breast cancer
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  • 19 Feb, 2024
Immediate Breast Reconstruction Following Mastectomy (IRMA)

Based on data from the US Surveillance, Epidemiology and End Result Program (SEER), the rates of nipple-sparing mastectomy (NSM) have risen 202% since 2009. In spite of the increasing popularity of IRMA, limited research has been done to identify complications in patients undergoing these procedures. Of particular importance is to …

mastectomy
breast reconstruction
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  • 19 Feb, 2024
Determination of Diastolic Dysfunction by Single Lead Electrocardiogram

It is a prospective, controlled, single-center, non-randomized, observational study. From September 2019 to December 2020, the study plans to prospectively include 400 patients aged 18 to 90 years. Every patients will undergo an echocardiographic examination with assessment diastolic dysfunction of the left ventricle, and registration of an electrocardiogram using a …

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  • 19 Feb, 2024
Advanced Sensor Based Functional ASsessmenTs in Axial Spondyloarthritis

This is an observational study using IMU sensors to measure the effects of biological therapy on spinal mobility and function in axial spondyloarthritis. Participants will undergo MRI scans before and after therapy in parallel to the sensor tests to establish correlation between changes in inflammatory signs and changes in spinal …

spondylarthritis
MRI Scan
axial spondyloarthritis
biological therapy
MRI
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  • 19 Feb, 2024
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis

Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.

endoscopic ultrasound
pancreatitis
pain management
celiac
neurolysis
  • 0 views
  • 19 Feb, 2024
Using the Movement and Electromyographical Analyses to Assess the Muscle Spasticity

This study intends to use an dynamometer and surface electromyography to objectively and quantitatively measure the corresponding force and electromyography signal generated when the hand joint receives stretching by doing circular motion, and further explore the differences and relationships of existing muscle spasm classification, kinetic and kinematic data, upper extremity …

spasticity
mental state examination
mini-mental state examination
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  • 19 Feb, 2024
CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer MIRAGE Study

This phase III trial studies compares CT-guided stereotactic body radiation therapy and MRI-guided stereotactic body radiation therapy (SBRT) in treating prostate cancer. Image-guided SBRT is a standard treatment for prostate cancer, which combines imaging of the cancer within the body with the delivery of therapeutic radiation doses produced on a …

adenocarcinoma of prostate
prostate cancer
ct of abdomen
cancer
positron emission tomography
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  • 19 Feb, 2024
Adductor Longus Tenotomy & the BKFO Test

The bent knee fall out test (BKFO) is a common test for hip adductor flexibility. It is unknown whether the BKFO actually tests the the adductors or potentially hip range of motion instead. In this study, the BKFO test is performed in the operating theater before and after an adductor …

  • 0 views
  • 19 Feb, 2024
Comparison of Rocuronium Induced Neuromuscular Blockade in Late Second Trimester Pregnant and Non-pregnant Women

The present study is to compare the onset and duration of rocuronium in late second trimester women and non-pregnant women undergoing general anesthesia.

neuromuscular blockade
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  • 19 Feb, 2024
Gender Identity and Own Body Perception

This study will provide valuable information on the neurobiological underpinning of gender dysphoria (GD) and the effects of sex hormones, and promises to uncover functional or structural neural patterns that could predict outcome in terms of body image and quality of life after cross-sex hormone treatment.

dysphoria
hormone therapy
sex hormones
  • 0 views
  • 19 Feb, 2024