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Found 1091 clinical trials
Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers

The purpose of this study is to develop a new drug treatment to reverse tumor resistance to radioiodine in BRAF mutant tumors so that radioiodine can be given to shrink tumors. This study is also being done to find out the highest doses of copanlisib and vemurafenib that, when given …

copanlisib
BRAF
braf v600 mutation
tumor progression
avid
  • 0 views
  • 19 Feb, 2024
  • 7 locations
18F-PSMA-1007 PET Imaging to Detect Primary Prostate Cancer

To study the added value of 18F-PSMA-1007 PET to mpMRI in the detection of local prostate cancer lesions.

positron emission tomography
digital rectal examination
multiparametric magnetic resonance imaging
pet/ct scan
  • 0 views
  • 19 Feb, 2024
  • 1 location
Effectiveness of a Mobile Neurofeedback for ADHD Youth

Objective: Verification of ADHD Treatment Effectiveness of Mobile Neurofeedback to Subjects of Child and Youth with ADHD. Method: Mobile Neurofeedback Program is implemented for 165 ADHD patients aged 8 to 15 to verify their effectiveness by conducting pre-post evaluation. Prior to the implementation of the intervention, we conduct a survey …

methylphenidate
neuropsychological test
sham treatment
magnetic resonance imaging of brain
neurofeedback
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension

This study is designed to investigate whether sympathoinhibition with moxonidine could provide added metabolic benefit compared to the second line therapy in the current guidelines.

body mass index
ace inhibitor
amlodipine 5 mg
hypertension
amlodipine
  • 0 views
  • 19 Feb, 2024
  • 1 location
Strain vs. Left Ventricular Ejection Fraction-based Cardiotoxicity Prevention in Breast Cancer

Comparing preventive effect of myocardial global longitudinal strain-based cardioprotective stragety (angiotensin receptor blocker prophylaxis) with left ventricular ejection fraction-based strategy in breast cancer patients treated with adjuvant trastuzumab.

anthracyclines
anthracycline
strain
trastuzumab
HER2
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cemiplimab Before and After Surgery for the Treatment of High Risk Cutaneous Squamous Cell Cancer

This phase I trial studies how well cemiplimab before and after surgery works in treating patients with high risk cutaneous squamous cell cancer. Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

squamous cell carcinoma of the skin
squamous cell carcinoma
oophorectomy
cancer therapy
extranodal extension
  • 0 views
  • 19 Feb, 2024
  • 1 location
Resting Full-cycle Flow Ratio (RFR) Versus Angiography to Guide Revascularization Strategy in Patients Undergoing Coronary Artery By-pass Grafting (CABG)

Different trials have shown that fractional flow reserve (FFR) could successfully guide revascularization in patients undergoing percutaneous coronary intervention (PCI). It is conceivable that a similar revascularization guidance could be useful also for surgical revascularization i.e. coronary by-pass graft (CABG). Experience learns that grafts placed on vessels with hemodynamically non-significant …

coronary artery stenosis
angiography
percutaneous coronary intervention
hyperemia
bypass graft
  • 0 views
  • 19 Feb, 2024
  • 1 location
Development of a Method for Continuous Absolute Non-inflating Measurement of Blood Pressure Using CardiacSense1BP

The primary objective of this research is to collect data for development of an algorithm for continuous, non-inflating measurement of absolute, long term Blood Pressure, using CardiacSense1BP device and to evaluate the safety of the CardiacSense1BP.

  • 0 views
  • 19 Feb, 2024
  • 1 location
ICG vs. HSI in Gastrointestinal Resections

In this study, gastrointestinal anastomoses are examined with a hyperspectral camera and after this the investigators use the Standard Routine ICG-Imaging. At the end, both methods will be compared..

  • 0 views
  • 19 Feb, 2024
  • 1 location
Liberation From Acute Dialysis

The goal of the LIBERATE-D clinical trial is to improve outcomes for patients recovering from dialysis-requiring acute kidney injury (AKI-D). The impact of a conservative dialysis strategy compared to standard clinical practice of thrice-weekly dialysis will be examined to help generate knowledge for how to guide delivery of dialysis to …

injury kidney
acute renal failure
vasoconstrictor
vasopressor
renal injury
  • 0 views
  • 19 Feb, 2024
  • 2 locations