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Found 67 clinical trials
Bone Pain in Multiple Myeloma- a Translational Study

While the survival expectancy of myeloma patients continues increasing due to the discovery of novel treatments, bone pain remains one of the main symptoms of this patient population, impairing their mood and quality of life. The aim of this study is to characterize the subjective experience of pain in myeloma …

bone pain
multiple myeloma
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  • 19 Feb, 2024
The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Use of indocyanine green will augment the accuracy of identification and resection of both primary solid malignancies as well as their pulmonary metastases, where applicable We will conduct a prospective feasibility study of pediatric patients with solid malignancies with or without lung metastatases who present at the time of initial …

cancer
metastatic malignancy
pulmonary metastasis
metastasis
ct scan
  • 0 views
  • 19 Feb, 2024
Serial Tumour Biopsies and Blood Biomarkers in Melanoma

Recent advances in understanding how cancer develops and spreads have led to effective new treatments and improved outcomes for patients with melanoma. However, we know that these new treatments do not work for all patients: some do not respond to them and some initially respond but then develop resistance. The …

cancer
advanced melanoma
metastatic malignant melanoma
blood test
cancer treatment
  • 0 views
  • 19 Feb, 2024
Optimizing Y90 Therapy for Radiation Lobectomy

HCC resection candidates with inadequate future liver remnant will be enrolled in this study. They will be treated with Y90 radioembolization to help grow the liver enough to undergo liver resection. There will be 2 Patient Groups. The first group of patients will be treated with Y90 dose and embolic …

cirrhosis
liver disease
angiography
liver diseases
radioembolization
  • 0 views
  • 19 Feb, 2024
Patient-Derived Xenografts to Reduce Cancer Health Disparities

This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic minorities. Understanding the genetic and response differences among racial/ethnic minorities may help researchers enhance the precision of therapeutic treatments.

bladder cancer
cancer
biospecimen collection
gastric cancer
lung cancer
  • 0 views
  • 19 Feb, 2024
Understanding the Transition from Normal Melanocytes to Nevus to Melanoma (NevustoMel)  

The primary objective of this study is to identify the molecular identity profiles of all cellular states that characterize the progression from benign nevi to malignant melanoma in CAYA patients with L/GCMN. The secondary objectives are:To longitudinally characterize the cell-free DNA (cfDNA) from CAYA patients.To improve the early diagnosis and …

  • 0 views
  • 02 Dec, 2024
Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population

This is an observational research study. Patients with rectal cancer can choose different courses of treatment. This study will follow these patients over the course of approximately six years, depending on their treatment. Patients will be monitored through clinic visits and survey assessments to see how they do, how they …

cancer
rectal cancer
proctectomy
  • 0 views
  • 19 Feb, 2024