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Found 1301 clinical trials
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …

monoclonal protein
autologous hematopoietic stem cell transplant
ixazomib
monoclonal antibodies
daratumumab
  • 0 views
  • 19 Feb, 2024
  • 8 locations
Dupilumab Asthma Sleep Study

Primary Objective: To assess the effect of dupilumab on sleep Secondary Objectives: To evaluate the effect of dupilumab on additional patient reported sleep outcomes To evaluate the effect of dupilumab on objective sleep assessment To evaluate the effect of dupilumab on asthma symptoms To evaluate the effect of dupilumab on …

forced expiratory volume
pulmonary function test
bronchodilator
fractional exhaled nitric oxide
polysomnography
  • 0 views
  • 19 Feb, 2024
  • 10 locations
Home Blood Pressure Study for Recent Stroke Survivors With High Blood Pressure *On Hold Due to Global Pandemic*

The purpose of this pilot study is to assess the feasibility of implementing a home blood pressure self-management program in a population of recent stroke survivors in the Washington, D.C. area. The investigators hypothesize that hypertensive stroke survivors in the Washington, DC area who participate in the Home Blood Pressure …

stroke
home blood pressure monitoring
systolic blood pressure
blood pressure management
hypertension
  • 0 views
  • 19 Feb, 2024
An Avatar-based Mobile Phone Intervention to Promote Health in African American MSM

The investigators propose to determine the efficacy of "My Personal Health Guide," a theory-based innovative talking relational human Avatar mobile phone application to engage HIV-positive AAMSM in adherence and retention in care. Providing an empathetic talking Avatar source of HIV-related information, motivation, and behavioral skills that is as private and …

  • 0 views
  • 19 Feb, 2024
Pilot Study of the Haymakers for Hope Fitness Program

This research study is assessing the effect of an exercise program on cancer survivors. The exercise program is Haymakers for Hope 16-week exercise program

brain metastasis
peripheral neuropathy
melanoma
metastasis
neuropathy
  • 0 views
  • 19 Feb, 2024
Genetic Testing for All Breast Cancer Patients (GET FACTS)

This study is designed to determine the impact of a novel genetic counseling method on surgical decisions in individuals with newly diagnosed breast cancer This research study involves an expedited and surgery-specific form of genetic counseling. The names of the study methods involved in this trial are/is: Quantitative genetic counseling …

genetic testing
breast cancer
cancer diagnosis
genetic counseling
breast carcinoma
  • 0 views
  • 19 Feb, 2024
Use Of Nfant(R) Technology Feeding System For Infants Less Than 30 Weeks GA

The purpose of the study is to utilize the objective data provided by the nfant suite of products, along with current NICU visual assessment and cue-based feeding practices, in order to determine if feeding performance outcomes and clinical decision making for individualized feeding plans for premature infants born less than …

premature birth
prematurity
  • 0 views
  • 19 Feb, 2024
The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia

Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal. This randomized control intervention pilot study will provide new evidence of the unexplored relationship between muscle strength and high BP in sarcopenia, and experimentally test the effects of an …

sarcopenia
strength training
resistance training
hypertension
  • 0 views
  • 19 Feb, 2024
Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

A Phase1/2a Study of Rigosertib plus Nivolumab in Stage IV Lung Adenocarcinoma Patients with KRAS Mutation who Progressed on First-Line Treatment

non-small cell lung cancer
bilateral oophorectomy
small cell lung cancer
stage iv lung adenocarcinoma
lung adenocarcinoma
  • 0 views
  • 19 Feb, 2024
A Novel Parent Education Program for Early Intervention

One in ten infants born in the USA is born preterm before 37 weeks of gestation and 50% of those will have motor and cognitive delays requiring intervention at school age. Because existing assessments do not reliably identify motor and cognitive delays early in development, many infants born preterm do …

  • 0 views
  • 19 Feb, 2024