Found 1256 clinical trials
Doxapram Therapy in Preterm Infants (DOXA Trial)
Doxapram is a respiratory stimulant that has been administered off-label to treat AOP. Doxapram, as add-on treatment, seems to be effective in treating AOP and to prevent invasive mechanical ventilation. It is unclear if a preterm infant benefit from doxapram treatment on the longer term.
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- 19 Feb, 2024
- 18 locations
Comparison and Clinical Utility of the Portable Pressure Measuring Device for Garment Pressure Measurement on Hypertrophic Scar by Burn Injury During Compression Therapy
The investigators developed a portable pressure measuring device using silicon piezoresistive pressure sensors. As PicoPress is the most accurate (i.e., lowest variation and error) manometric sensor for pressure measurement, the investigators used it to compare and examine the accuracy of the proposed device regarding in vitro pressure measurements.
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- 19 Feb, 2024
- 1 location
Liaqun-Application of the Belle.AI Dermatological Image Reference System for Patient Diagnosis in an Active Clinical Setting
The sponsor aims to compare the diagnoses made by primary care providers (such as doctors, nurse practitioners, and physician assistants) with the support of the AI tool compared to a panel of dermatologists, who are setting the gold standard.
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- 27 Apr, 2026
- 1 location
Regulated Expiratory Breathing Method During Childbirth
Despite a positive experience both reported by women and midwives, investigators have so far only subjective feedback without objective measurable clinical impact. As a result, investigators are conducting this scientific study whose main objective is: To Evaluate the impact of a regulated expiratory breathing method on childbirth process .
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- 19 Feb, 2024
- 1 location
Adenoid Cystic Carcinoma and Carbon Ion Only Irradiation
Despite their slow growth, re-irradiation is often necessary due to the high metastatic risk. Patients are usually irradiated with photons or, as here at the Heidelberg University Hospital, with a combination of carbon ions and photons. So far, there is no data from Europe available for the sole irradiation with …
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- 19 Feb, 2024
- 1 location
Does Point of Care Ultrasound Change Needle Insertion Location During Routine Bedside Paracentesis?
The primary endpoint will be whether POCUS yielded a change in the needle insertion site, as defined by a location greater than 5cm from the anatomic site, at least 20% of the time. The results will further our understanding of POCUS in improving procedural safety, thereby adding to the currently …
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- 19 Feb, 2024
- 1 location
The Acute Effects of Pragmatic Manual Therapy on the Range of Motion of Shoulder Joint
Beneficial intervention among the four trials and other previously reported beneficial in improving the shoulder joint range will be combined in and termed as pragmatic interventions protocols. Pragmatic interventions on subjects with restricted range in shoulder pathology will be tested through similar design.
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- 19 Feb, 2024
- 1 location
The Use of plasmaJet During Operative Laparoscopy for Endometriosis
The PlasmaJet system uses argon plasma which is released as kinetic, light and / or thermal energy. In this way the instrument can be applied within three functions, namely cutting, vaporizing and coagulating.
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- 19 Feb, 2024
- 1 location
Effects of Transcranial Direct Current Stimulation Associated With Cognitive Training in Alzheimer's Disease
According to the Diagnostic and Statistical Manual of Mental Disorders (DSM 5), mnemonic dysfunction in AD must be related to aphasia, apraxia, agnosia, or changes in executive function. The clinical picture of the disease can be described as mild, moderate and severe. In the mild phase, the patient is disoriented …
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- 19 Feb, 2024
- 1 location
Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients
Brigatinib may continue beyond disease progression per RECIST v1.1 until loss of clinical benefit, unacceptable toxicity, patient or physician decision to discontinue, or death as per SmPC recommendations. Patient accrual is expected to be completed within 1.5 years excluding a run-in-period of 4-6 months.
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- 19 Feb, 2024
- 15 locations