Found 1246 clinical trials
Assessment of Lateral and Vertical Tissue Displacement Obtained by the Retraction Cord and Diode Laser
In fixed prosthodontic treatment, deflection of gingival tissues for diagnosis or making an impression is one of the important phases. Gingival displacement is defined as "displacement of gingival tissues both in vertical and lateral dimensions". Lateral retraction displaces the tissues so that an adequate bulk of impression material can be …
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- 19 Feb, 2024
- 1 location
Primary Organoid Models and Combined Nucleic Acids Therapeutics for Anti-HPV Treatments
The International Agency for Cancer Research of World Health Organization (WHO) classified a dozen of HPV related high-risk cancer types, and recognized cervical cancer as the most common HPV-related disease. HPV 16 and 18 are responsible for 70% of cervical cancers. Due to the few symptoms of cervical cancer, women …
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- 19 Feb, 2024
- 1 location
PERSONAE - a Personalized Online Treatment of Depression
What challenges do participants experience when using the PERSONAE intervention?Researchers will compare PERSONAE to Treatment As Usual (a standard, one-size-fits-all treatment) to evaluate whether PERSONAE is more effective in treating mild to moderate depression.
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- 10 Aug, 2025
- 1 location
Oral EPI-7386 in Patients With Metastatic Castration-Resistant Prostate Cancer
This is a phase I, clinical research study of EPI-7386, an investigational drug being studied as a treatment for patients with prostate cancer. All patients in the study will receive EPI-7386. Since this is the first study of EPI-7386 in humans, there is no information about how it affects people …
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- 19 Feb, 2024
- 5 locations
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids
Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease. T2D and heart disease share many common risk factors such as aging, obesity and unhealthy lifestyle. Paradoxically however, while lowering blood LDL, commonly known as "bad cholesterol", …
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- 19 Feb, 2024
- 1 location
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)
Thus, it is urgent to develop innovative models of PA, closer to patients and adjusted to the patients' routines, to engage and change patients' physical activity levels, enhancing HRQoL. iLiFE might be promising as it focuses on establishing new behaviours, within selected contexts to stimulate home-based PA. Therefore, iLiFE will …
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- 19 Feb, 2024
- 1 location
Inspiratory Muscle Training Versus Calf Muscle on Venous Function
Fourty-two volunteer patients with venous insufficiency will include in the study were randomly divided into three groups as inspiratory exercise, calf muscle exercise and control. While the control group will receive only compression therapy, the inspiratory exercise group will apply inspiratory muscle training consisted of strengthening exercise in addition to …
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- 19 Feb, 2024
- 1 location
ROCO - Self-help for People With Psychological Distress Due to the Covid-19 Situation
As part of the ROCO project, the University of Bern is investigating an online self-help program for people who are psychologically distressed due to the situation surrounding Covid-19.
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- 19 Feb, 2024
- 1 location
Ultrasound Features of Dupuytren's Disease (Micro in DD)
This study will provide some insight into the use of US for DD and will primarily try to evaluate different parameters measurable with US that can be used as potential prognostic biomarkers.
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- 07 May, 2025
- 1 location
Perioperative Toripalimab and Endostatin for Stage II Melanoma: A Phase II Trial (FUMS-EDJS2024)
This is a Phase II clinical trial to evaluate the efficacy and safety of perioperative toripalimab (anti-PD-1) combined with recombinant human endostatin (Endostar) as postoperative adjuvant therapy in patients with clinical stage II cutaneous or acral malignant melanoma. The study aims to answer:Does this combination improve the 2-year recurrence-free survival …
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- 14 Jun, 2025