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Found 2,823 clinical trials

Z Zai Lab

A Trial of ZL-1201 in Subjects With Advanced Cancer

First in Human, Phase I Trial of Anti-CD47 Antibody ZL-1201 in Subjects with Advanced Cancer

18 years and older All Phase 1
A Astellas Pharma Global Development, Inc.

Single Ascending Dose of ASP3772 Study in Japanese Healthy Male and Female Adults and Single Ascending Dose Study of ASP3772 in Comparison With PPSV23 in Japanese Elderly Male and Female Subjects

The purpose of this study is to evaluate the safety and tolerability of 3 different dose levels of ASP3772 administered subcutaneously or intramuscularly to Japanese healthy adults 20 to 49 years of age. This study will also evaluate the safety and tolerability of 3 different dose levels of ASP3772 administered …

20-85 years All Phase 1
A Anabela Silva

Effect of Nervous System Mobilization on Athletes' Performance

This study aims to compare the effects of two diferente doses of nervous system mobilization on athletes performance.

18 years and older All Phase N/A
S Samantha Greeley, BS

Prospective Robotic Global Research Study (PROGRESS)

The purpose of this study is to prospectively review outcomes of patients who have surgery with the ExcelsiusGPS robotics system in order to analyze screw placement accuracy. Patient demographics, intraoperative data and radiographic imaging to determine screw placement accuracy will be collected and reviewed. This information will be compared in …

18-85 years All Phase N/A
x xinan sheng, doctor.

A Study of RC48-ADC(Antibody Drug Conjugate) and JS001 to Evaluate the Safety and Pharmacokinetics of Subjects With Locally Advanced or Metastatic Urothelial Cancer

This is an open-label, single-arm, Phase Ib/II investigator-initiated trial of RC48-ADC combined with JS001 to evaluate the safety and pharmacokinetics of subjects with locally advanced or metastatic urothelial cancer

18 years and older All Phase 1/2
L Lynn Ghijselings, MD

TTNS Versus Sham Therapy for Children With iOAB (TaPaS Part I)

Part I of the TaPaS trial forms part of a twofold clinical RCT: Part 1) A prospective RCT comparing the efficacy of transcutaneous tibial nerve stimulation (TTNS) with TTNS sham therapy for children with idiopathic overactive bladder on clinical and patient reported outcomes (PROMS). Part 2) A prospective RCT comparing …

5-12 years All Phase N/A
E Erica Robichaud

Teaching Novel Values-Based Skills to Improve Long-Term Weight Loss

This NIDDK funded R01 project is a randomized controlled clinical trial to compare the efficacy of an intervention based on Acceptance and Commitment Therapy (ACT) and a Self-Regulation (SR) intervention on weight loss maintenance over a 30-month period. All participants will first complete a well-validated online weight loss intervention (months …

25-70 years All Phase N/A
C Cheryl Duzenli, PhD

Carbon-Fibre Accessory (CARA) for Supine Breast Positioning to Reduce Toxicity in Whole Breast Radiotherapy

This trial is designed to assess the efficacy of a novel carbon-fibre adjustable reusable accessory (CARA) for breast support to reduce skin toxicity and unwanted normal tissue dose in comparison to the current clinical standard for supine breast support during whole breast RT.

18 years and older All Phase N/A
S Stephen Baldassarri, M.D.

Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-nave smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …

21-55 years All Phase N/A
A April Fenner, RN

Evaluation of Stool Microbiome Using HyGIeaCare Prep

Stool samples will be collected before and during the HyGIeaCare procedure and the samples will be sent for microbiome evaluation.

18-80 years All Phase N/A

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