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Found 1305 clinical trials
Cysteamine for Asthma

The purpose of this study is to see if a medicine called Cysteamine, given along with standard asthma care, will improve asthma symptoms and lung function.

allergen
rhinitis
corticosteroids
prick skin
skin prick
  • 14 views
  • 20 Sep, 2024
  • 1 location
Training Single Arm

The pulmonary hypertension is a disease, which tends to a progredient right heart failure. Although there was a large progress in development of medical therapy, the quality of life, the physical efficiency and the prognosis of the patients are still limited. The aim of the study is to examine the …

right heart catheterization
medical therapy
hypertension
right ventricular failure
heart failure
  • 0 views
  • 19 Feb, 2024
High-Speed Yoga and Executive Function

The purpose of this research study is to establish if a novel high-speed yoga program which incorporates visual cues can make a positive change in the participant's ability to make decisions and move as measured by several cognitive, balance and functional tests. It has been shown that yoga can improve …

neuromuscular diseases
hoehn and yahr scale
cardiovascular disease
cognitive assessment
cancer
  • 0 views
  • 19 Feb, 2024
CD19 Chimeric Antigen Receptor (CAR) T Cells for Adults With Recurrent or Refractory B Cell Malignancies

In this protocol, the investigators hypothesize that modifying the process of producing CAR+ T-cells can help to improve responses and reduce toxicities. Building on previous in vitro studies that have shown successful production of CAR+ T-cells using a new production approach, the investigators are now studying the ability to produce …

ejection fraction
flow cytometry
absolute lymphocyte count
recurrent disease
apheresis
  • 0 views
  • 19 Feb, 2024
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC.

castration-resistant prostate cancer
cancer
measurable disease
metastatic castration-resistant prostate cancer
rimiducid
  • 0 views
  • 19 Feb, 2024
Endoscopic Sinus Surgery in Recurrent Acute Rhinosinusitis

The aim of this study is to find out if endoscopic sinus surgery improves the quality of life in patients suffering from recurrent acute rhinosinusitis. Our main outcome is the difference between the average change in disease-specific SNOT-22 quality of life questionnaire scores (from baseline to 5-6 months follow-up) between …

congestion
acute sinusitis
antibiotic therapy
rhinosinusitis
corticosteroids
  • 0 views
  • 19 Feb, 2024
Mobile Microwave-based Diagnosis and Monitoring of Stroke

This is a prospective, open, multicentre trial that will enrol patients with clinical signs of stroke in the acute phase admitted for CT scan. The study assesses the diagnostic capability and safety of Strokefinder MD100.

ischemic stroke
hemorrhagic stroke
ct scan
stroke
  • 0 views
  • 19 Feb, 2024
Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

To investigate the potential efficacy of dupilumab in the treatment of moderate to severe chronic hepatic pruritus.

dupilumab
chronic pruritus
  • 0 views
  • 19 Feb, 2024
The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Vaccination

Hypothesis: Infections other than HIV can cause LN inflammation and collagen damage to the fibroblastic reticular cell network (FRCn), which will lead to CD4 T cell depletion and impaired vaccine responses. This protocol will study yellow fever vaccine (YFV) in two cohorts of people, one from Uganda and the other …

yellow fever
vaccination
immunosuppressive
  • 0 views
  • 19 Feb, 2024
Predictors of Response in Chronic Stroke

This study will validate a predictive model that uses demographics, functional status, neurophysiology, neuroanatomy, and other potential biomarkers to predict the likelihood of a clinically significant change in impairment at the end of a robot assisted therapy intervention.The study will include magnetic resonance imaging (MRI), transcranial magnetic stimulation (TMS), and …

arm exercises
transcranial magnetic stimulation
arm exercise
MRI
chronic stroke
  • 0 views
  • 19 Feb, 2024