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Found 1327 clinical trials
CPX-351 in Higher Risk Myelodysplastic Syndromes

Study of the efficacy of CPX-351 treatment in patients with higher risk myelodysplastic syndromes : as first line treatment or after hypomethylating agents failure

cytarabine
serum total bilirubin
prednisone
cardiovascular disease
systemic steroids
  • 0 views
  • 19 Feb, 2024
  • 12 locations
Student-delivered Telehealth Program for COVID-19 Education and Health Promotion

The purpose of this study is to ensure effective health management among community-living older adults during unprecedented times, such as the current COVID-19 pandemic.

covid-19
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cryoablation Atezolizumab/Nab-paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer

Drugs used in chemotherapy, such as nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

paclitaxel
stage iv breast cancer
systemic chemotherapy
cancer
prognostic stage iiib breast cancer ajcc v8
  • 0 views
  • 19 Feb, 2024
  • 1 location
Low Dose Ruxolitinib in Combination With Methylprednisolone

This study is to determine the efficacy and safety of combined Low dose Ruxolitinib With Methylprednisone as Initial Therapy for the aGVHD(acute graft-versus-host disease )

blood disorder
hematologic disorders
corticosteroids
cancer
ruxolitinib 5 mg
  • 0 views
  • 19 Feb, 2024
  • 1 location
Home Blood Pressure Study for Recent Stroke Survivors With High Blood Pressure *On Hold Due to Global Pandemic*

The investigators hypothesize that hypertensive stroke survivors in the Washington, DC area who participate in the Home Blood Pressure Monitoring program will have a greater reduction in mean systolic blood pressure (SBP) from baseline to 3 months, as measured by automated office blood pressure (AOBP), as compared to usual care.

systolic blood pressure
home blood pressure monitoring
stroke
hypertension
blood pressure management
  • 0 views
  • 19 Feb, 2024
  • 1 location
Restrictive Use of Dexamethasone in Glioblastoma

However, steroids are also linked to a multitude of adverse side effects that may affect survival of GBM patients such as major immunosuppression. The use of steroids during radiotherapy is associated with reduced overall- and progression-free survival and has been identified as an independent poor prognostic factor.

dexamethasone
neurologic symptoms
immunosuppression
glioblastoma multiforme
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants

The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants.

radiopharmaceuticals
  • 0 views
  • 19 Feb, 2024
  • 1 location
Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial

The purpose for this study is to determine whether left posterior wall isolation (PWI) in addition to pulmonary vein isolation (PVI) is effective as ablation strategy for persistent atrial fibrillation (AF).

antiarrhythmic drug
atrial fibrillation
pulmonary vein isolation
conversion to sinus rhythm
persistent atrial fibrillation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Characterisation of the Nasal Microbiome in Patients With N-ERD

Here, the investigators plan to analyse the nasal microbiome in these patients and to compare it to nasal samples from CRSwNP and CRSsNP patients as well as healthy controls (in total 80 subjects). This will provide insights into potential differences in the microbiome as compared to other CRS patients and …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Wells and Enteric Disease Transmission Trial (WET - Trial)

These cases of GI can cause a significant burden in terms of health care costs and lost work/school days, as well as increased risk to developing longer term health complications. This impact is magnified when accounting for vulnerable populations such as children under the age of 5, the elderly and …

  • 0 views
  • 19 Feb, 2024
  • 1 location