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Found 1410 clinical trials
A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease

Treatment period (up to 16 weeks).Follow-up period (4 weeks). The number of visits will be up to 13.

  • 0 views
  • 20 Jul, 2026
  • 1 location
Study on the Ability of Virtual Reality Glasses in Anxiety and Pain Reduction in 50 Women Undergoing Amniocentesis or Feticide

Both amniocenteses and especially feticide are procedures that incorporate both anxiety and pain. As anxiety and pain can be reduced when using a distraction, The investigators speculate that the use of virtual reality glasses during these procedures will elevate both anxiety and pain.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Patients with unequivocal recurrence (first or greater) established by MRI and meeting inclusion and exclusion criteria, will be eligible for OKN-007 treatment on this protocol.

  • 0 views
  • 19 Feb, 2024
  • 3 locations
HCV Reinfection After DAA Therapy in PWID in Belgium

Individuals with active injecting drug abuse with a chronic HCV infection who have achieved end of treatment response (ETR; defined as non-detectable HCV RNA at end of treatment) to any interferon-free DAA combination will be included in this multicenter interventional study.

hepatitis
  • 0 views
  • 19 Feb, 2024
  • 10 locations
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

They will take it in weeks 1, 2, 4, and 5. The timing may be changed. Starting the first day of radiation, participants will take temozolomide by mouth once a day until they complete radiation.

cancer
therapeutic agents
gliosarcoma
temozolomide
external beam radiotherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland : A Monocentric Nested Cohort Randomized Controlled Trial: The SORT Study.

A nested cohort Randomised Controlled Trial (ncRCT) design will be applied to divide patients into the two groups. The health and wellbeing of the young people will be assessed at baseline and then followed-up for 24 months to see whether they transition to AMHS or are discharged or referred to …

psychiatric disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI

After implantation different hemodynamic indices of paravalvular leakage will be assessed. At 1 month a cardiac MRI will be performed to quantify the amount of paravalvular leakage. Standardized clinical follow-up will take place at discharge, 30 days, 3 months and yearly up to 5 years.

aortic valve stenosis
stenosis
cardiac mri
transcatheter aortic valve implantation
symptomatic aortic stenosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Multi-CAR-T Cells Targeting B Cell Lymphomas

Clinical response and development of a simplified and standardized lentiviral vector and cell production protocol will be investigated. This is a phase I/II trial enrolling patients from multiple clinical centers.

  • 0 views
  • 19 Feb, 2024
  • 3 locations
Cryoballoon Pulmonary Vein Isolation for Atrial Fibrillation With Heart Failure

Pulmonary vein isolation is an established method for the treatment of symptomatic AF in patients with normal heart function and has been shown to be more effective than drug therapy. Recently, radiofrequency ablation has shown a positive effect in patients with AF and HF. POLAR-HF has been designed to investigate …

fibrillation
atrial fibrillation
heart failure
persistent atrial fibrillation
pulmonary vein isolation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Adductor Canal Block (ACB) Versus ACB /Saphenous Block in Patients Undergoing Anterior Cruciate Ligament Repair

Thus, the possibility of incomplete block of the saphenous nerve (most important nerve in knee innervations) cannot be excluded.

ligament repair
local anesthesia
local anesthetics
anaesthesia
knee surgery
  • 0 views
  • 19 Feb, 2024
  • 1 location