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Found 483 clinical trials
Pelvic Floor Magnetic Stimulation in Women With Idiopathic Overactive Bladder

In clinical practice, Bladder Traininhg (BT) and Magnetic stimulation (MS) are frequently used together in the treatment of women with idiopathic overactive bladder (OAB). Up to our knowledge, there is no study evaluating the combined effect of magnetic stimulation and bladder training in women with idiopathic OAB in the literature. …

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  • 19 Feb, 2024
A Trial of Neoadjuvant mXELOXIRI Versus CRT in the EMVI Positive LARC

Extramural Vascular Invasion Positive(EMVI+) is a high risk of distant metastasis for locally advanced rectal cancer(LARC) after resection. The study is to evaluate the efficacy and safety of XELOXIRI as neoadjuvant chemotherapy alone for EMVI+ LARC in contrast to the efficacy of standard Chemoradiotherapy (CRT).

chemoradiotherapy
rectal carcinoma
renal function
adenocarcinoma of rectum
cancer
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  • 19 Feb, 2024
Prophylactic Infusion of Calcium Gluconate Reducing the Rate of Hypocalcaemia After Total Thyroidectomy

Post-total thyroidectomy hypocalcaemia is a common complication with the rate ranging from 13-49% in a meta-analysis. However, the rate in UMMC in 2018 and 2019 were 40% and 23% respectively. It lead to prolonged hospital stay and patient dissatisfaction in the event of hypocalcaemia. Research question: Does prophylactic intravenous calcium …

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  • 19 Feb, 2024
MRI Assessing Clinical Usability of STrategically Acquired Gradient Echo on Human Participants

The study's purpose is to validate STAGE images and, when applicable, their equivalence to conventional MRI through an assessment by a trained certified neuroradiologist in a clinical setting. For STAGE images without conventional equivalent, the neuroradiologist will determine if their contrasts, intensities, and quality are sufficient and meet expectations for …

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  • 19 Feb, 2024
PAXG Out in the Country

The objective of this study is to assess the reproducibility of PAXG regimen as first-line/primary chemotherapy in daily clinical practice in Pancreatic Ductal Adenocarcinoma (PDAC) borderline resectable, locally advanced or metastatic patients out of a large volume center.

neutrophil count
pdac
ductal adenocarcinoma
absolute neutrophil count
cisplatin
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  • 19 Feb, 2024
Multicenter Perspective Study: Clinical Evaluation of the Persona MC With Preservation or Sacrifice of the PCL

Prospective, multicenter study on the Total Knee Prosthesis available on the market "Persona Medial Congruent knee". Primary endpoint -Evaluation of the survival of the implant after 5 years of follow-up Secondary endpoints Evaluation of the survival of the implant at 10 years of follow up. Evaluation of clinical and radiographic …

knee pain
patellectomy
polyarthritis
knee arthroplasty
osteoarthritis
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  • 19 Feb, 2024
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-sch nlein Purpura

The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with Henoch-schnlein purpura.

aldesleukin
interleukin
interleukin 2
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  • 19 Feb, 2024
Music as Analgesia During Neonatal Circumcision

Neonatal circumcision is one of the most frequently performed and more painful procedures. Sharara et al (2017) showed the combination of EMLA + Sucrose + Ring Block provides the highest standard of pain management. A combination which has been adopted by practitioners who perform circumcisions at the normal nursery at …

emla
analgesia
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  • 19 Feb, 2024
Safety of Manganese Restriction in Neonatal Parenteral Nutrition

Participants will be <= 32 weeks gestational age (GA) neonates randomized to parenteral nutrition (PN) prepared with standard dose trace elements or to PN prepared with standard trace elements minus manganese.

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  • 19 Feb, 2024
At-Risk for Type 1 Diabetes Extension Study

This study is an extension of the NIH-sponsored AT-Risk (TN-10) type 1 diabetes study (NCT 01030861). Teplizumab-treated and placebo-treated participants in the NIH trial who develop clinical type 1 diabetes after the conclusion of that trial, are eligible to enroll and receive teplizumab treatment within one year of diagnosis of …

type 1 diabetes mellitus
diabetes
teplizumab
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  • 19 Feb, 2024