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Found 1062 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

alzheimer's disease
mental state examination
mini-mental state examination
apolipoprotein e4
Accepts healthy volunteers
  • 32 views
  • 20 Sep, 2024
  • 127 locations
Study in Subjects With Relapsed/Refractory Follicular Lymphoma

This is a multicenter, double-blind, active-controlled, randomized, 3-stage, biomarker enrichment design featuring early futility stopping and sample-size re-estimation with safety run-in designed to evaluate the efficacy and safety of tazemetostat in combination with R2 in subjects with R/R FL, who have completed at least 1 prior systemic chemotherapy, immunotherapy, or …

follicular lymphoma
monoclonal antibodies
cancer therapy
tubal ligation
monoclonal protein
  • 0 views
  • 19 Feb, 2024
  • 8 locations
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients  

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

lung cancer
small cell lung cancer
squamous non-small cell lung cancer
platinum-based chemotherapy
docetaxel
  • 0 views
  • 19 Feb, 2024
  • 55 locations
MicroNet-covered Stent System for Stroke Prevention in All Comer Carotid Revascularization

All-comer study of unselected patients suitable for carotid artery revascularization to evaluate the feasibility, efficacy and safety of first line endovascular revasculariztion using MicroNet covered stent (CGuard) in the treatment of consecutive symptomatic and increased-stroke-risk asymptomatic carotid lesions that require revascularization by Neurovascular Team decision.

nascet method
atherosclerosis
stroke
ischemic attack
stenosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Moisturizer Containing Licochalcone A, Decanediol, L-carnitine and Salicylic Acid in Reducing Relapsing of Acne  

Moisturizer containing the active ingredients of licochalcone A, decanediol, L-carnitine, and salicylic acid may be beneficial in alternative treatment of acne in maintenance phase. This study aims to evaluate the efficacy and safety of moisturizer containing the active ingredients of licochalcone A, decanediol, L-carnitine, and salicylic acid during the maintenance …

  • 0 views
  • 21 Mar, 2025
  • 2 locations
Project MiNT: Assessing the Impact of Food & Video-Based Nutrition Education on Patients With Poorly Controlled Diabetes

This pragmatic randomized controlled trial will assess the efficacy of medically tailored meals and medical nutrition therapy via telehealth on clinical outcomes for patients with poorly controlled type 2 diabetes. The goal of these interventions is to improve outcomes for patients with diabetes by impacting self-care behaviors and diet self-efficacy …

nutritional support
nutrition education
medical nutrition therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
The TAPS Trial - Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence

This multicenter open-label randomized controlled trial is set up to evaluate the effect of fetoscopic laser surgery on the gestational age at birth for monochorionic twin pregnancies diagnosed with twin anemia-polycythemia sequence. Half op the patients will be treated with fetoscopic laser surgery, while the other half will be managed …

  • 0 views
  • 19 Feb, 2024
  • 5 locations
Comparison of Eligible TAVI-valves - Cohort B

The study performs head-to-head comparison of two TAVI-valves: Sapien and Myval.

tavi
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Communication Enhancing Intervention to Improve Patients' Perception of Physiotherapy Consultations

The aim of this study is to test the effectiveness of a single training session in communication skills at improving patients' perceptions of physiotherapy consultations.

physiotherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Music as Analgesia During Neonatal Circumcision

Neonatal circumcision is one of the most frequently performed and more painful procedures. Sharara et al (2017) showed the combination of EMLA + Sucrose + Ring Block provides the highest standard of pain management. A combination which has been adopted by practitioners who perform circumcisions at the normal nursery at …

emla
analgesia
  • 0 views
  • 19 Feb, 2024
  • 1 location