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Found 142 clinical trials
ZYNRELEF® for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy (HeronBariatric)  

Secondary Objectives:To evaluate additional efficacy parameters, including opioid load, in this study population.To determine the impact of ZYNRELEF® on the cost of pain management.To assess the time taken to resume exercise after discharge.To assess the adverse events reported following the use of ZYNRELEF®.

  • 0 views
  • 19 Feb, 2024
  • 2 locations
A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)

Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 1-17 years with Systemic Juvenile Idiopathic Arthritis (sJIA) in order to identify the dose and regimen for adequate treatment of this population. Secondary Objective: To describe the pharmacodynamics (PD) profile, the efficacy, and the long term safety …

arthritis
glucocorticoids
disease modifying antirheumatic drugs
rheumatism
fever
  • 0 views
  • 19 Feb, 2024
  • 30 locations
An Open-label Ascending Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA)

Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 2-17 years with Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) in order to identify the dose and regimen for adequate treatment of this population Secondary Objective: To describe the pharmacodynamic (PD) profile, the efficacy and the long-term safety of …

arthritis
anti-rheumatic drugs
sarilumab
rheumatoid factor
antirheumatic
  • 0 views
  • 19 Feb, 2024
  • 33 locations
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cardiac surgery
cognitive deficit
comatose
heart surgery
memory impairment
  • 0 views
  • 19 Feb, 2024
Lavender Aromasticks for Pain Control

The purpose of this randomized pilot study is to collect preliminary data on the impacts of lavender essential oil aromatherapy on the patient-reported quality of pain management provided for the vascular surgery patient population. The investigators hypothesize that individuals who use a lavender aromastick as a part of their pain

complementary therapy
essential oil
vascular surgery
pain relieving
lavender oil
  • 0 views
  • 19 Feb, 2024
Telehealth Pain Self-Management for Employed Adults

The E-TIPS trial will evaluate an evidence-based, telehealth pain self-management intervention compared to standard care (a waitlist) for chronic pain in adults with physical disabilities who are employed.

physical disability
chronic pain
  • 0 views
  • 19 Feb, 2024
Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control

Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.

toxic epidermal necrolysis
cesarean section
postoperative pain
transcutaneous electrical nerve stimulation
analgesia
  • 0 views
  • 19 Feb, 2024
SPRINT Peripheral Nerve Stimulation for the Treatment of Back Pain

The SPRINT PNS System was cleared by the FDA for up to 60 days of use in the back and/or extremities for the management of acute and chronic pain.

electrical stimulation
chronic pain
low back pain
back pain
peripheral nerve stimulation
  • 0 views
  • 19 Feb, 2024
Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture

The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo

ache
delirium
hip fracture
ropivacaine
  • 0 views
  • 19 Feb, 2024
A Study to Compare Two Techniques for Pain Control After Bariatric Surgery

The purpose of this study is to compare the postoperative pain and other clinical outcomes in patients who, during bariatric surgery, will be injected with a local anesthetic (Ropivacaine) through two different techniques.

ropivacaine
local anesthetics
postoperative pain
local anesthetic
local anesthesia
  • 0 views
  • 19 Feb, 2024