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Found 660 clinical trials
Effect of Different Treatments on the Prognosis of Early Cervical Cancer: A Multicenter Prospective Real-world Study

To observe the effects of different treatments on the oncological outcome and complications of early cervical cancer (2018 FIGO stage IA1 with lymphovascular space invasion and IA2-IIA2 cervical cancer). This study prospectively collecting enrolled cervical cancer patients clinical data and outcome from June 2020 to June 2025.

uterine cervix
adjuvant therapy
cervical cancer
cervical disease
cancer
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  • 19 Feb, 2024
RASopathy Biorepository

Each syndrome in this group of disorders has unique phenotypic features, but there are many overlapping features including facial features, heart defects, cutaneous abnormalities, cognitive delays, and a predisposition to malignancies. This research study proposes to collect and store human bio-specimens from patients with suspected or diagnosed RASopathies.

heart defects
genetic testing
cancer
  • 0 views
  • 19 Feb, 2024
Urinary and Sexual Dysfunctions Evaluation After Rectal Resection

Advances in the treatment of rectal cancer over the past two decades have improved survival and significantly reduced surgery-related morbidity. As a result, post-treatment quality of life (QoL) issues have become increasingly important.

chemo-radiotherapy
cancer
total mesorectal excision
carcinoma
rectal neoplasm
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  • 19 Feb, 2024
Efficacy of Chemopreventive Agents on Disease-free and Overall Survival in Patients With Pancreatic Ductal Adenocarcinoma: The CAOS Study

The evidence on the value of aspirin, statins, metformin, beta-blocking ACE inhibitors agents as chemopreventive agents in patients with pancreatic ductal adenocarcinoma is limited. The aim of this study is to assess whether regular use of aspirin, statins, metformin, angiotensin converting enzyme (ACE)-inhibitors and beta-blocking agents use, before diagnosis, after …

metformin
metastasis
chemoradiotherapy
adjuvant therapy
immunostimulant
  • 0 views
  • 19 Feb, 2024
Characterization of Methylation Patterns in Hepatocellular Carcinoma

This study is being performed as part of the development process of the Liver EpiCheck test which includes the identification of different methylation profiles in HCC (hepatocellular carcinoma) patients compare to cancer free control in blood samples

fatty liver
ascites
cirrhosis
cancer
carcinoma
  • 0 views
  • 19 Feb, 2024
Endoscopic Resection of Large Colorectal Polyps: An Observational Cohort Study

It addresses an important challenge in the prevention of colorectal cancer: how to safely and effectively remove large polyps.

colorectal cancer
colorectal polyps
prevention of colorectal cancer
endoscopic resection
cancer
  • 0 views
  • 19 Feb, 2024
EsophaCap for the Detection of Early Esophageal Carcinoma

This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.

early detection
esophageal carcinoma
esophagogastroduodenoscopy
cancer
carcinoma
  • 0 views
  • 19 Feb, 2024
Diagnosis Treatment Status and Prognosis of Cholangiocarcinoma in China: a Multicenter Two-way Non-intervention Study

This is a multicenter, two-way, non-intervention study. the main purpose: Understand the current status of diagnosis and treatment of cholangiocarcinoma patients in China and observe the effect of different treatment options on patient recurrence and long-term survival Secondary purpose: Exploring the actual clinical treatment situation and its compliance with the …

cancer
cholangiocarcinoma
  • 0 views
  • 19 Feb, 2024
Development and Validation for Predicting Inadequate Bowel Preparation

High-quality colonoscopy is considered the gold standard for the detection and prevention of colorectal cancer, and its efficacy is predicated on optimal colon cleansing.However, about 18%-35% of patients were still reported to suffer inadequate bowel preparation.

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  • 19 Feb, 2024
PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies

The main aim of the study is to set up an observational cohort with NAFLD (Non-alcoholic fatty liver disease) at different stage of disease (from simple steatosis to cirrhosis and/or HCC-Hepatocellular carcinoma) and for comparative purpose a cohort of subjects with diabetes and/or obesity and/or other risk factors (i.e. psoriasis, …

alcoholic fatty liver
fatty liver
inflammatory bowel disease
carcinoma
diabetes
  • 0 views
  • 19 Feb, 2024