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Found 5900 clinical trials
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers.

lung cancer
lymphoma
solid tumor
erbb1
pd-l1
  • 0 views
  • 19 Feb, 2024
  • 39 locations
Altered Tumor Oxygenation by Metformin a Potential Step in Overcoming Radiotherapy Resistance in LACC

Poor tumor oxygenation (hypoxia) is an established negative prognostic and predictive factor in locally advanced cervical cancer (LACC). Hypoxia-modifying measures implemented in the clinic are lacking.

renal function test
hypoxia
adenosquamous carcinoma
adenocarcinoma
squamous cell carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
RISI in the Treatment of Recurrent Metastatic SCC of Thoracic Inlet Lymph Nodes

The malignant tumor at the thoracic entrance is difficult to be surgically removed, and radiotherapy or radiotherapy based comprehensive treatment is often chosen at the initial diagnosis.

cancer
hypertension
squamous cell carcinoma
carcinoma
salvage therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

Lenvatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

erythropoietin
beta human chorionic gonadotropin
bilirubin levels
lenvatinib
primary tumor
  • 8 views
  • 19 Feb, 2024
  • 1 location
A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET

A Phase II trial aiming to assess the safety and activity of the combination of cabozantinib plus lanreotide in gastroenteropancreatic (GEP) and thoracic neuroendocrine tumor (NET): The LOLA trial

carcinoma in situ
intestinal neuroendocrine tumor
squamous cell skin cancer
major surgery
prrt
  • 0 views
  • 19 Feb, 2024
  • 1 location
IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

This is a phase 1/2 multicenter, multi-regional, open-label, first-in-human study of IBI3014 in participants with unresectable locally advanced or metastatic solid tumors.

  • 0 views
  • 22 Aug, 2025
  • 2 locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

HER2
exhausted
cancer
measurable disease
advanced solid tumor
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

head and neck cancer
cancer
cancer of the head
measurable disease
cetuximab
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

HER2
solid tumor
fulvestrant
measurable disease
her2-negative breast cancer
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

The participants are being treated with Tumor Treating Fields (TTFields) for malignant glioma, and this type of treatment may cause skin-related side effects. This study will test whether using clindamycin and triamcinolone topical lotions can prevent skin-related side effects of TTFields.

triamcinolone topical
malignant glioma
glioblastoma multiforme
clindamycin
glioma
  • 0 views
  • 19 Feb, 2024
  • 7 locations