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Found 553 clinical trials
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Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging

However, the incidence of human papillomavirus (HPV) related oropharyngeal carcinomas is increasing. It is known that HPV+ and HPV- tumors have a different reaction to (chemo)radiotherapy. The exact mechanisms underlying these differences is not yet known but might be caused by changes in vascularity.

ct perfusion
tobacco products
carcinoma
ct scan
chemoradiotherapy
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  • 19 Feb, 2024
  • 1 location
Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers

This will include patients with either Human papilomavirus-associated (HPV-associated) oropharyngeal cancer (OPC), Human papilomavirus-negative (HPV-negative) OPC or Base of Skull HNC. Single centre prospective interventional phase I/II study (main study) made up of 3 independent arms (on the condition of success of the feasibility stage).

advanced head and neck carcinoma
neutrophil count
squamous cell carcinoma of head and neck
carcinoma
head and neck carcinoma
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  • 19 Feb, 2024
  • 1 location
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy.

neutrophil count
robotic surgery
docetaxel
chemo-radiotherapy
human papillomavirus
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  • 19 Feb, 2024
  • 1 location
Prospective Comparison of Pull-PEG and Pull-PEG With Gastropexy

The study aims to compare the conventional pull-percutaneous endoscopic gastrostomy (pull-PEG) with a pull-PEG with gastropexy suture regarding the peristomal infection rate.

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  • 19 Feb, 2024
  • 1 location
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants

This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.

lung disease
social interactions
social interaction
diabetes
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  • 19 Feb, 2024
  • 1 location
Ventilation With Supraglottic Airway Devices

Airo-Q Self Pressurized airway device with Blocker will be compared with I-Gel in anesthetized adult female patients undergoing elective surgeries to discuss the influence of different head and neck positions on the performance of both devices. Oropharyngeal leak pressure, peak inspiratory pressure, ventilation score and fiber-optic view will be assessed …

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  • 19 Feb, 2024
  • 1 location