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Found 1256 clinical trials
Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma

The objective of this study is to evaluate, in patients diagnosed with prostate cancer who undergo radical prostatectomy and who require postoperative radiotherapy, tolerance in terms of acute and chronic GU and GI toxicity and efficacy in terms of biochemical control and survival, as well as of quality of life, …

adenocarcinoma of prostate
digital rectal examination
bone scan
ct scan
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 19 locations
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

This clinical trial is studying two immunotherapy drugs (nivolumab and ipilimumab) given together as a possible treatment for INI1-negative tumors.

dyspnea at rest
karnofsky performance status
measurable disease
ipilimumab
pulse oximetry
  • 0 views
  • 19 Feb, 2024
  • 1 location
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

total cavopulmonary connection
  • 0 views
  • 19 Feb, 2024
  • 1 location
Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment

The modified masks will be made from masks that are already available as well as filters available in the pulmonary department at the Oklahoma City VA Health Care System

coronavirus infection
covid-19
  • 0 views
  • 19 Feb, 2024
  • 1 location
CPX-351 in Higher Risk Myelodysplastic Syndromes

Study of the efficacy of CPX-351 treatment in patients with higher risk myelodysplastic syndromes : as first line treatment or after hypomethylating agents failure

serum total bilirubin
leukemia
systemic steroids
lenalidomide
chronic myelomonocytic leukemia
  • 0 views
  • 19 Feb, 2024
  • 12 locations
Cryoablation Atezolizumab/Nab-paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer

Drugs used in chemotherapy, such as nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

stage iv breast cancer
pd-l1
monoclonal antibody therapy
breast tumor
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Student-delivered Telehealth Program for COVID-19 Education and Health Promotion

The purpose of this study is to ensure effective health management among community-living older adults during unprecedented times, such as the current COVID-19 pandemic.

covid-19
  • 0 views
  • 19 Feb, 2024
  • 1 location
Low Dose Ruxolitinib in Combination With Methylprednisolone

This study is to determine the efficacy and safety of combined Low dose Ruxolitinib With Methylprednisone as Initial Therapy for the aGVHD(acute graft-versus-host disease )

blood disorder
allogeneic hematopoietic stem cell transplant
methylprednisolone
ruxolitinib 5 mg
corticosteroids
  • 0 views
  • 19 Feb, 2024
  • 1 location
Home Blood Pressure Study for Recent Stroke Survivors With High Blood Pressure *On Hold Due to Global Pandemic*

The investigators hypothesize that hypertensive stroke survivors in the Washington, DC area who participate in the Home Blood Pressure Monitoring program will have a greater reduction in mean systolic blood pressure (SBP) from baseline to 3 months, as measured by automated office blood pressure (AOBP), as compared to usual care.

systolic blood pressure
hypertension
blood pressure management
home blood pressure monitoring
stroke
  • 0 views
  • 19 Feb, 2024
  • 1 location
Restrictive Use of Dexamethasone in Glioblastoma

However, steroids are also linked to a multitude of adverse side effects that may affect survival of GBM patients such as major immunosuppression. The use of steroids during radiotherapy is associated with reduced overall- and progression-free survival and has been identified as an independent poor prognostic factor.

glioblastoma multiforme
neurologic symptoms
immunosuppression
dexamethasone
  • 0 views
  • 19 Feb, 2024
  • 1 location