Found 1087 clinical trials
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function
Secondary Aims Compare the efficacy of Everolimus plus Mycophenolate Mofetil versus Tacrolimus plus Mycophenolate Mofetil therapy as measured by the following: Biopsy-confirmed acute rejection Hyperlipidemia Proteinuria % regulatory T-cells in circulation NODAT [New Onset Diabetes mellitus After Transplant], hypertension and malignancy Tolerance measured by gene profiling at year 1, 2 …
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- 19 Feb, 2024
- 1 location
Effectiveness of a Cardiovascular Risk Intervention Program in Patients With Schizophrenia (PRISCA)
Secondary measures: they will be determined, at baseline and at six-month follow-up, four cardiovascular risk factors as well: hypertension, hypercholesterolemia, hyperglycaemia and smoking, according with the latest recommendations of the Program of preventive activities and health promotion (PAPPS) of the Spanish Society of Family and Community Medicine.
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- 19 Feb, 2024
- 1 location
Preoperative Percutaneous RVAD to Preemptively Treat Right Heart Failure Post-LVAD
Since RVF is difficult to predict and can have harmful effects such as increased ICU stay, adverse outcomes, and mortality, it could be beneficial to preemptively treat patients through preoperative percutaneous right ventricular assist device (RVAD) placement to prevent RVF.
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- 19 Feb, 2024
- 1 location
Effects of a Multimodal Exercise Program on Physical Performance and Muscle Function in Middle-aged Patients With T2DM
The findings are expected to support early intervention strategies for healthy aging and serve as a valuable reference for clinical practice and the development of public health policies.
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- 02 Dec, 2025
- 3 locations
Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland : A Monocentric Nested Cohort Randomized Controlled Trial: The SORT Study.
The investigators will then evaluate what impact the different transition experiences have on young people's health and wellbeing, and whether the process of Managed Transition has any benefits as compared to usual care.
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- 19 Feb, 2024
- 1 location
Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults
The investigators hypothesize that people with chronic stroke will show a slower rate of acquiring this leg skill as compared to healthy adults. The investigators also hypothesize that co-applying brain stimulation with 12 sessions of exercise training will enhance skill learning of this leg task for people with chronic stroke …
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- 19 Feb, 2024
- 1 location
Acute Atrial Fibrillation and Flutter Treated Electively
After the months follow-up all patients are subsequently monitored for a maximum of five years for need of medical interventions due to atrial fibrillation of atrial flutter. New antiarrhythmics such as flecainide are not prescribed during the first month.
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- 19 Feb, 2024
- 4 locations
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
On Arm B of the study, research participants will receive CAR T cells directed at B7H3 and CD19, a marker on the surface of B lymphocytes, following the hypothesis that CD19+ B cells serving in their normal role as antigen presenting cells to T cells will promote the expansion and …
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- 19 Feb, 2024
- 1 location
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma
To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.
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- 19 Feb, 2024
- 1 location
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma
This trial is a multi-center, phase III, randomized (1:1) clinical trial. The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.
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- 19 Feb, 2024
- 1 location