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Found 593 clinical trials
Evaluation of AZD8154 Concentrations in Blood

This study is intended to evaluate the systemic pharmacokinetic (PK) characteristics and the safety of AZD8154 following administration of the Monodose DPI formulation compared with the administration of the nebuliser suspension.

bilateral salpingectomy
hysterectomy
oophorectomy
follicle stimulating hormone
forced expiratory volume
  • 0 views
  • 19 Feb, 2024
  • 1 location
Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

The purpose of this project is to realize a randomized open-label study (EudraCT number: 2020-000120-19) to evaluate the safety and the anti-tumor activity of peptide(s)-based immunotherapy in an umbrella window pre-operative opportunity phase II study in patients with squamous cell carcinoma of the head and neck.

carcinoma in situ of the cervix
platelet count
neutrophil count
io102
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia"

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orally once daily in pediatric patients with newly diagnosed chronic phase Ph+ CML (ND CML) and pediatric patients with Ph+CML who have received at least one prior TKI therapy (R/I CML), …

growth factor
chronic myeloid leukemia
biologic agent
chronic phase chronic myeloid leukemia
molecular diagnosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

metastatic head and neck squamous cell cancer
measurable disease
squamous cell carcinoma of head and neck
carcinoma
cetuximab
  • 0 views
  • 19 Feb, 2024
  • 1 location
Illusory Movements in Patients With Burns

Background. Large burns are the cause of extensive skeletal muscle devastation. The possibilities of rehabilitation of such patients are very limited, which contributes to the risk of metabolic failure and long-term musculoskeletal disorders. Illusory movements are a relatively new method of physiotherapy, which through functional proprioceptive stimulation enables the integration …

insulin
catabolic state
musculoskeletal disorders
insulin resistance
  • 0 views
  • 19 Feb, 2024
  • 1 location
Investigating the Effect of Diroximel Fumarate on Glutathione in Schizophrenia (FORTUNE)

Schizophrenia is a condition that causes symptoms like delusions, hallucinations, reduced motivation and muddled thinking. It is a common, severe and disabling psychiatric illness affecting about 1/100 (1%) of people. It is ranked the third most disabling illness worldwide. Six in seven patients do not recover from the illness in …

  • 0 views
  • 06 May, 2025
  • 1 location
Cysteamine for Asthma

The purpose of this study is to see if a medicine called Cysteamine, given along with standard asthma care, will improve asthma symptoms and lung function.

skin prick test
pulmonary function test
rhinitis
allergen
skin prick
  • 14 views
  • 24 Nov, 2025
  • 1 location
Effect of Cannula Size on Oxygen Saturation During Nasal High Flow Therapy in Newborns

Treatment with nasal high flow therapy (NHF) is an increasingly popular method of respiratory support in newborns. Safe and effective use of NHF requires selection of an appropriate nasal prong-to-nares ratio because leak can influence the delivered pressure. To the best of our knowledge, this is the first study to …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study

Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia. In this interventional study we want to investigate a "cause-effect" relationship between mastication and cognition in humans. A total of eighty (80) participants, …

prosthetic rehabilitation
cognitive changes
dementia
mini-mental state examination
mental state examination
  • 0 views
  • 19 Feb, 2024
  • 1 location
Evaluation of an Early Support Programme in Orthophony

Prospective, interventionnal with minimal risks and constraints, multicentric, non-randomized, open study, to measure the impact of an early support programme in speech and language therapy for vulnerable children (PAPEV-ortho), in children born very prematurely or very hypotrophically, on the incidence of language and communication deficits at the corrected age of …

intrauterine growth retardation
premature birth
  • 0 views
  • 19 Feb, 2024
  • 4 locations