Found 1399 clinical trials
Preoperative Percutaneous RVAD to Preemptively Treat Right Heart Failure Post-LVAD
Subjects who consent to the study will undergo pre-operative placement of an RVAD, which will be left in up to 72 hours postoperatively. The type of RVAD (Impella RP or ProtekDuo) inserted will be determined by patient needs and venous access and will be up to the discretion of the …
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- 19 Feb, 2024
- 1 location
Longitudinal Immune-phenotyping of HCC Following MK-3475
Translational analyses performed for liver tissue samples in the sub-study will be harmonized with the analyses on liver tissue samples collected in the main study.
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- 19 Feb, 2024
- 1 location
Altered Tumor Oxygenation by Metformin a Potential Step in Overcoming Radiotherapy Resistance in LACC
This study is a randomized, phase II, open label study in patients with LACC where patients are randomized to standard cisplatin-based chemoradiotherapy +/- Metformin. Metformin will be started one week prior to the start of chemoradiotherapy, and will be continued throughout the entire radiation treatment. Tumor oxygenation will be evaluated …
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- 19 Feb, 2024
- 1 location
A Prospective Clinical Study of Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert AEG
Methods: A prospective, single-center, one-arm study will be performed. Patients who have been diagnosed with Siewert type esophagogastric junction adenocarcinoma and meet the eligibility criteria will be included in the study and undergo the transthoracic single-hole assisted laparoscopic radical gastrectomy.
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- 19 Feb, 2024
- 1 location
The Young Heart Study
Psychological support will be provided to address stress that impairs quality of life, depression or anxiety to fully optimize the lifestyle component. These sessions will be done virtually in order to comply with social distancing until in person sessions can resume.
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- 19 Feb, 2024
- 1 location
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
Participants in all cohorts will receive the same dose of atezolizumab (1200 mg every 3 weeks). In the first stage for each cohort, 8 participants will be enrolled and if no participants respond to treatment, enrollment to that cohort will be closed. If 1 or more participants respond to treatment, …
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- 19 Feb, 2024
- 1 location
Effectiveness of a Primary Care Clinical Ultrasound Classroom
Methods: quasi-experimental study, with before / after design, with a control group and one year of follow-up. 20 family doctors working in primary care Health Centers and with a list of patients over 800 will be included and a control group of similar characteristics will be selected, in terms of …
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- 19 Feb, 2024
- 1 location
RCT of Ovarian Function Following Intraovarian Injection of PRP
Consenting women with evidence of poor ovarian reserve will be randomly assigned to treatment with either Platelet Rich Plasma (PRP) or Platelet Poor Plasma (PPP).
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- 19 Feb, 2024
- 1 location
COVID-19 and the Healthy Minds Program for Educators
Every 7-days over the 4-week intervention period participants in both conditions will complete the same set of measures. A full battery of measures will be administered a second time post-test, following the 4-week intervention period. Three-months after post-test, a follow-up assessment will be conducted.
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- 19 Feb, 2024
- 1 location
The Effect of The Personalized Patient Engagement Plan on Diabetes Management
This study evaluates the effect of Personalized Patient Engagement Plan on diabetes management in patients with at least six months of Type-2 Diabetes. The research is planned to be carried out as an experimental study with pretest-posttest control groups. Half of the participants will receive the Personalized Patient Engagement Plan; …
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- 19 Feb, 2024
- 2 locations