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Found 86 clinical trials
Myocardial Contrast Echocardiography in Septic Patients

Myocardial microcirculatory alterations may be involved in the pathogenesis of acute cardiac dysfunction or septic cardiomyopathy in septic patients. The investigators study the cardiac function (systolic and diastolic) with two-dimensional echocardiography (TTE), and the myocardial microcirculation with contrast echocardiography (MCE) and sulphur hexafluoride microbubbles Sonovue injection in ICU septic patients.

shock
serum lactate
organ failure
cardiomyopathy
lactate level
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  • 19 Feb, 2024
Premie DCD Imaging Intervention Study

This study will leverage a current longitudinal study of brain development in preterm children. In the Miller/Grunau Trajectories study, preterm children are returning for follow-up at 8-9 years. At this appointment, children undergo MRI and neurodevelopmental testing. Children who are identified with DCD at this appointment will be invited to …

  • 0 views
  • 19 Feb, 2024
Minocycline in MS: Confirmation of Benefit

This is an open-label, single-arm clinical trial. Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging (MRI) with at least two brain T2 lesions which are at least 3 mm …

demyelination
multiple symptoms
health screening
oligoclonal bands
minocycline
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  • 19 Feb, 2024
OCT Evaluation of Early Vascular Repair in Patients With Non ST Elevation Acute Coronary Syndrome (NSTE-ACS)

This is a prospective study of a new generation of drug-eluting stent in the treatment of non ST elevation acute coronary syndrome (NSTE-ACS). The purpose of this study was to evaluate the extent of early vascular repair in NSTE-ACS patients after receiving the new generation of drug-eluting stents, and the …

stenosis
optical coherence tomography
ischemia
neointima
dapt
  • 0 views
  • 19 Feb, 2024
Trauma Specific Frailty Index

Increasing age is a known predictor of morbidity and mortality after a traumatic injury with worst outcomes seen in patients with age greater than 65 years (9). Geriatric trauma patients are a unique cohort of patients who are highly prone to develop decompensated state following the stress of traumatic event …

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  • 19 Feb, 2024
ICG Fluorescence Imaging in Lower Extremity Amputation Patients

This is a non-randomized prospective study of 30 patients scheduled to undergo lower extremity amputation (below the knee, through the knee or above the knee) evaluating bone perfusion and viability using indocyanine green (ICG) fluorescence imaging at several steps during surgical procedure.

fluorescence imaging
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  • 19 Feb, 2024
ICG Fluorescence Imaging in Trauma Patients

This will be a prospective observational trial to better understand the range and variation associated with bone/soft tissue perfusion in fracture patients and examine the relationship between perfusion, measured using quantitative Indocyanine green (ICG) fluorescence and complications such as surgical site infection (SSI), persistent SSI, and fracture nonunion.

debridement
fracture care
closed fracture
wound care
internal fixation
  • 0 views
  • 19 Feb, 2024
Pre-hospital Tourniquet in Extremity Injury

Objective: Primary Objective: To compare outcomes of patients with extremity injuries presenting with or without pre-hospital tourniquet placement. 2.2. Study Outcome Measures Primary Outcome: Incidence of arrival in shock (SBP <90) Secondary Outcomes: Demographics, comorbidities, mechanism of injury, cause of injury, diagnosis codes, procedure codes, ISS, AIS, operative management vs. …

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  • 19 Feb, 2024
Accuracy of TCOM vs NIRS in Predicting Wound Outcomes in Patients Treated With or Without Revascularization

The primary purpose of this project is to compare the accuracy of transcutaneous oxygen monitoring and near infrared spectroscopy in assessing cutaneous oxygen levels in chronic wounds of patients following revascularization procedures as well as those with conservatively managed chronic wounds. This study will also compare the efficiency and practicality …

lower extremity wound
near infrared spectroscopy
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  • 19 Feb, 2024
Complex Decongestive Therapy on Distal Radius Fracture

Trauma results in inflammatory reactions accompanied by high protein edema. Trauma can also reduce the carrying capacity of the lymphatic system below normal lymphatic load, leading to exposure of lymphedema.

distal radius fracture
complex decongestive therapy
  • 0 views
  • 19 Feb, 2024