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Found 79 clinical trials
A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants

The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants.

radiopharmaceuticals
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  • 19 Feb, 2024
Education Program for Care Home Staff

The competence of care home staff in dementia care is highly influential to the quality of care that adversely affects both people living with dementia and staff and in Mainland China where knowledge on dementia among care home staff was generally poor and this area is under-researched.

dementia
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  • 19 Feb, 2024
Effects of Transcranial Direct Current Stimulation Associated With Cognitive Training in Alzheimer's Disease

Alzheimer's disease (AD) is characterized by a progressive decline in cognitive functions, interfering with autonomy and independence. According to the Diagnostic and Statistical Manual of Mental Disorders (DSM 5), mnemonic dysfunction in AD must be related to aphasia, apraxia, agnosia, or changes in executive function.

aphasia
mental state examination
cognitive disorder
cognitive training
behavioral symptoms
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  • 19 Feb, 2024
Orange Juice and Glycaemic Control in Type 2 Diabetes Mellitus

The aim of the project is to study the impact of the intake of a single serving of 100% orange juice on glycaemic control in male patients with pre-existing type 2 diabetes mellitus. In addition, immunological parameters and Alzheimer disease related biomarkers will be assessed to examine the chronic inflammatory …

plasma glucose
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  • 19 Feb, 2024
Equality in Caregiving

The primary goal of this pilot clinical trial is to establish the readiness of an intervention addressing the unique challenges facing lesbian, gay, bisexual, and transgender (LGBT) informal caregivers of person living with dementia (PLWD), and geared toward achieving caregiver mastery in this high-risk population, for a larger efficacy trial.

dementia
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  • 19 Feb, 2024
Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)

Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by double-blind, randomized adjunctive treatment with clonazepam or pregabalin for persistent symptoms.

panic disorder
depo-provera
implanon
nuvaring
major depressive disorder
  • 0 views
  • 19 Feb, 2024
A Study to Evaluate the Safety Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease

This study is a multicenter, double blind, randomized, placebo-controlled study to evaluate the safety, tolerability and immunogenicity of different doses, regimens and combinations of Tau targeted vaccines in participants with early Alzheimer's Disease.

amyloidosis
acetylcholinesterase inhibitor
cognitive impairment
combinations
dementia
  • 0 views
  • 19 Feb, 2024
  • 0 views
  • 29 Nov, 2024
  • 1 location
Virtual Trail 03

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  • 0 views
  • 19 Feb, 2024
  • 4 locations
Trial For DQ

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  • 0 views
  • 19 Feb, 2024
  • 5 locations