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Found 656 clinical trials
Validation of the Italian Version of the PRO-CTCAE

In particular, for the first time this study will validate the tool for individual types of cancer and will provide information on psychometric properties based on the type of treatment used in clinical practice.

cancer
  • 0 views
  • 19 Feb, 2024
Reorganization of the Healthcare System During COVID-19 Pandemic: Impact on Management of Patients With Exocrine Pancreatic Cancer

An increased risk of severe COVID-19 infection in cancer patients is suggested in several Chinese series. Cancer care structures quickly reorganized to limit high-risk situations (diagnostic procedure, major surgery, cytotoxic poly-chemotherapy) and use alternatives such as on-hold chemotherapy.

pancreatic cancer
cancer
adenocarcinoma
pancreatic adenocarcinoma
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
A Multivariate Index Assay for Ovarian Cancer Risk Assessment in Women With Adnexal Mass and High-Risk Germline Variants

The objective of this project is to validate the sensitivity, specificity, positive predictive value and negative predictive values of the AMRA blood test for assessing risk of cancer in women at high risk for ovarian cancer, due to the presence of a symptomatic adnexal mass.

  • 0 views
  • 19 Feb, 2024
Using Deep Learning Methods to Analyze Automated Breast Ultrasound Images to Establish a Diagnosis Therapy Assessment and Prognosis Prediction Model of Breast Cancer.

The purpose of this study is using a deep learning method to analyze the automated breast ultrasound (ABUS) imagings, establish and evaluate a diagnosis, therapy assessment and prognosis prediction model of breast cancer. The model would provide important references for further early prevention, early diagnosis and personalized treatment.

ultrasound breast
early detection
  • 0 views
  • 19 Feb, 2024
AXillary Surgery After NeoAdjuvant Treatment

The optimal surgical axillary staging technique in patients who convert from the clinically positive to clinically negative lymph node status under neoadjuvant therapy (cN+ ycN0) remains to be clarified. Different strategies (axillary lymph node dissection, sentinel node biopsy, targeted axillary dissection) are currently used in different countries. A prospective analysis …

invasive breast cancer
sentinel lymph node biopsy
lymphadenectomy
sentinel node
fine needle aspiration
  • 0 views
  • 19 Feb, 2024
Antler Plate on Preventing Mammary High-risk Lesions From Malignant Development

This study aims to prove whether antler disk extract can be put into clinical practice to prevent breast precancerous lesions from developing into cancer.

  • 0 views
  • 19 Feb, 2024
Prediction of Therapeutic Response of Apatinib in Recurrent Gliomas

Apatinib, also known as YN968D1, is a small-molecule tyrosine kinase inhibitor (TKI) that selectively binds to and inhibits vascular endothelial growth factor receptor 2 (VEGFR-2). This study aims to collect clinical, radiological and histopathology imaging including detailed radiological data, survival data, clinical parameters, molecular pathology and images of HE slices …

vascular endothelial growth factor receptor 2
glioma
platelet count
postoperative complication
vegf
  • 0 views
  • 19 Feb, 2024
Clinical and Genetic Analysis of ROP

Retinopathy of Prematurity (ROP) is a vascular disease affecting the retinas (back of the eye) of low birth weight infants. Although it can be treated effectively if diagnosed early, it continues to be a leading cause of childhood blindness in the United States and throughout the world. The investigators feel …

strabismus
blindness
genetic analysis
pediatric
prematurity
  • 0 views
  • 19 Feb, 2024
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants

This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.

social interaction
diabetes
lung disease
social interactions
  • 0 views
  • 19 Feb, 2024
The Genetics and Vascular Health Check Study (GENVASC) Aims to Help Determine Whether Gathering Genetic Information Can Improve the Prediction of Risk of Coronary Artery Disease (CAD)

The Genetics and Vascular Health Check study (GENVASC) is a large study run in conjunction with Clinical Commissioning Groups and Primary Care practices across Leicester, Leicestershire and Northamptonshire. The purpose of GENVASC is to help determine whether gathering genetic information can improve the prediction of risk of Coronary Artery Disease …

arteriopathy
coronary disease
cardiovascular disease
  • 0 views
  • 19 Feb, 2024