Found 1297 clinical trials
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.
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- 19 Feb, 2024
PB2452 in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure
These populations will be enrolled based on separate inclusion criteria.
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- 19 Feb, 2024
Semantic Feature Analysis Treatment for Aphasia
This randomized controlled comparative effectiveness study examines manipulation of a key component of an established and efficacious treatment for naming impairments in aphasia, along with cognitive and brain correlates of treatment success. Study participants will be randomly assigned to one of two treatment conditions comparing two different versions of Semantic …
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- 19 Feb, 2024
Transcranial Static Magnetic Field Stimulation (tSMS) in Amyotrophic Lateral Sclerosis (ALS).
Clinical status will be tested before, during and after the stimulation period. Moreover, cortical excitability will be tested by transcranial magnetic stimulation (TMS) before and after the stimulation period.
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- 19 Feb, 2024
Effect of Academic Detailing to Reduce Opioid Prescribing in Dentistry
The cohort of 90 dentists who are enrolled to the CE will be randomized into two groups upon enrollment. One of these groups, half of the cohort, will receive the academic detailing. A report will be written highlighting key findings from this project and best practices for treating patients after …
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- 19 Feb, 2024
Efficacy of Different Toothbrushes and Hygiene Regimen
The differences in the criteria evaluated will be submitted to Fisher's exact test ( = 0.05) and their performance at different times will be evaluated by the Mann-Whitney test ( = 0.05).
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- 19 Feb, 2024
Prospective Clinical Trial of Onlay-carrying Patients
A record of the type of onlay will be made with respect to its extension, tooth or teeth to be treated, the material of clothing and the substrate on which the adhesion and cementing method, as well as the type of antagonist.
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- 19 Feb, 2024
Prehabilitation for Gastrectomy
Currently, the most effective strategy seems to be a trimodal prehabilitation which includes: 1) Nutritional support 2) Psychological support and 3) Physical training.
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- 19 Feb, 2024
A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Once the MTD is determined, it is planned that an additional 15 participants will be enrolled in Phase 1b of this study for additional experience with safety and efficacy, and to determine the recommended Phase 2 dose (RP2D) which may or may not be different from the MTD.
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- 19 Feb, 2024
Stability and Outcomes of Non-displaced Lisfranc Injuries
In this multicenter cohort study, the stability of non-displaced Lisfranc injuries as well as their outcomes will be evaluated.
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- 19 Feb, 2024