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Found 427 clinical trials
Advanced Geriatric Evaluation and Quality of Life in Colorectal Cancer Surgery

Colorectal cancer (CRC) disproportionately affects patients aged 70 years and older. Surgery is the main treatment modality for CRC, but is associated with increased risk of postoperative morbidity, disability and loss of health related quality of life (HRQL).Frailty is an age related state of functional decline and considered to be …

cancer surgery
metastatic colorectal cancer
colorectal cancer
  • 0 views
  • 19 Feb, 2024
Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19)

People with cancer may be at higher risk of poor outcomes with COVID-19 infection. This observational study aims to describe the clinical course of COVID-19 infection in people with cancer and evaluate the utility of antibody and antigen tests for COVID-19. The results of this study will inform clinical practice …

covid-19
lymphoma
acute respiratory syndrome (sars)
SARS
cancer
  • 0 views
  • 19 Feb, 2024
Malnutrition in Chronic Gastrointestinal Diseases Cross-sectional Study

Malnutrition and muscle wasting are common consequences of life-threatening, chronic diseases of the gastrointestinal tract. Such diseases include liver cirrhosis, chronic pancreatitis and short bowel syndrome. Malnutrition and muscle wasting increase the risk of complications, reduce the life expectancy and impair the quality of life. The development of malnutrition and …

pancreatic resection
liver cirrhosis
muscle wasting
endoscopic ultrasound
computed tomography
  • 0 views
  • 19 Feb, 2024
Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer

In this study, investigators utilize a radiomics prediction model to predict the tumor response to neoadjuvant chemoradiotherapy (nCRT) before the nCRT is administered for patients with locally advanced rectal cancer (LARC). Previously, the radiomics prediction model has been constructed based on the radiomics features extracted from pretreatment Magnetic Resonance Imaging …

adjuvant chemotherapy
adenocarcinoma
adjuvant
metastasis
cancer
  • 0 views
  • 19 Feb, 2024
Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID 19 Prediction of Outcome

To ascertain globally the changes in the cytokines involved and TLRs/KIR activation in patients admitted to the hospital with a COVID-19 diagnosis, and the changes after initiation of the different therapies

covid-19
cytokines
  • 0 views
  • 19 Feb, 2024
A Clinical Study of Pyrotinib in Patients of Advanced Colorectal Cancer With Her2 Variation

To Observe the Efficacy and Safety of Pyrotinib Maleate in Patients With Advanced HER2 Variation Colorectal Cancer

platelet count
immunohistochemistry
ejection fraction
pyrotinib
blood transfusion
  • 0 views
  • 19 Feb, 2024
RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal Cancer

In this study, investigators utilize a radiopathomics integrated Artificial Intelligence (AI) supportive system to predict tumor response to neoadjuvant chemoradiotherapy (nCRT) before its administration for patients with locally advanced rectal cancer (LARC). By the system, whether the participants achieve the pathologic complete response (pCR) will be identified based on the …

adjuvant chemotherapy
adenocarcinoma
adjuvant
metastasis
cancer
  • 0 views
  • 19 Feb, 2024
Heart Failure Monitoring With Eko Electronic Stethoscopes

This proof-of-concept study will evaluate the feasibility of the Eko DUO to measure signals relevant to heart failure (HF) decompensation, as well as the feasibility to develop an algorithm to model hemodynamic filling pressures in HF patients under active decompensation in a cardiac intensive care unit (CICU) or coronary care …

acute decompensated heart failure
heart failure
adhf
decompensated heart failure
hemodynamic measurements
  • 0 views
  • 19 Feb, 2024
Detection of Metabolite Biomarkers for the Early Diagnosis and Prognosis of Cow's Milk Allergy in Children

In this study, fecal and urine samples will be collected from children diagnosed with : IgE mediated cow's milk allergy, suspected of a cow's milk allergy, but with negative diagnosis IgE mediated food allergy other than cow's milk healthy brothers and sisters of the first three groups A subset of …

milk allergy
early diagnosis
food allergy
allergy in children
  • 0 views
  • 19 Feb, 2024
A Single-cell Transcriptome Study in Patients With Non-Hodgkin's Lymphoma

Using single-cell RNA sequencing, this study will explore the heterogeneity of lymphoma inside and outside the lymph node, identify tumor specific molecular markers and cell subgroups, explore the differences in tumor microenvironment composition, and provide a basis for diagnosis and precision treatment.

non-hodgkin lymphoma
lymphoma
hodgkin's disease
  • 0 views
  • 19 Feb, 2024