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Found 472 clinical trials
Venous Disease in Pediatric Population

Chronic venous disease (CVD) is widespread in adult subjects of western countries and is responsible of important morbidity and healthcare costs. CVD has never been extensively studied in pediatric population where the early pathophysiological alterations may occur undetected. The aim of this study is to assess the prevalence of CVD …

pediatric
venous disease
  • 0 views
  • 19 Feb, 2024
Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800 an Inhibitor of the Heat Shock Protein HSP90

While it is currently being tested for solid cancers, no preclinical study has yet demonstrated its effectiveness in acute lymphoblastique leukemia (ALL). The investigators wish to study the effects of NVP-BEP800 on two different types of ALL (T and B-ALL).

  • 0 views
  • 19 Feb, 2024
Design and Implementation of the Pediatric Liver Transplantation Biobank

The purpose of the pediatric liver transplant biobank is to systematically collect clinical specimens from pediatric end-stage liver disease. It is expected to contribute to the research and development of paediatric end-stage liver disease in the future.

liver transplant
pediatric
liver disease
  • 0 views
  • 19 Feb, 2024
Prospective Analysis of the Feasibility of the PASCAL Spacer Technology for Transcatheter Mitral Valve Repair in an All-comers Cohort

To identify changes on mitral valve morphology and functionality by the application of the PascalTM in MR.

mitral valve repair
  • 0 views
  • 19 Feb, 2024
Cerebral Morbidity After Radiation Therapy for Brain Tumors

This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.

cognitive dysfunction
anaplastic astrocytoma
cognitive impairment
glioblastoma
sarcomas
  • 0 views
  • 19 Feb, 2024
COVID-19 in Cancer Patients: Evaluation of Clinical Course and Impact on Oncological Care Including Biobanking

The COVIDHELP study will prospectively evaluate the yet unknown clinical course of the COVID-19 infection in cancer patients and document the impact of potential infrastructural limitations on cancer care of COVID-19 positive patients. All patients consenting will provide peripheral blood samples for prospective biobanking with the aim of investigating immune …

covid-19
cancer care
cancer
  • 0 views
  • 19 Feb, 2024
Patient Reported Outcome Measures After Treatment of Skin Cancers on the Face

Patients diagnosed with primary melanoma and/or SCC and/or infiltrative basal cell carcinoma on the face subjected to surgical treatment (excision or Mohs Surgery) will be included. All patients will receive questionnaires.

squamous cell carcinoma
carcinoma
skin cancer
mohs surgery
cancer
  • 0 views
  • 19 Feb, 2024
Correlation Between Oxidative Stress Status and COVID-19 Severity

During the new COVID-19 pandemic physicians all over the world have faced different challenges .Oxidative stress is a probable cause of multi organ failure in this setting which never has been evaluated in COVID-19 infection to the best of knowledge.Present study aimed to evaluate oxidative stress marker and redox system …

elisa
multiple organ failure
  • 0 views
  • 19 Feb, 2024
Neoadjuvant Chemotherapy in Borderline Resectable and Locally Advanced Pancreatic Cancer

Eligible patients are treated with neoadjuvant chemotherapy possibly followed by surgical exploration and resection. All Norwegian centres performing pancreatic surgery have agreed to collaborate in this trial. The assignment of the medical intervention is not at the discretion of the investigator, but follow the national Norwegian guidelines regarding diagnostic work …

pancreatic adenocarcinoma
cancer
pancreatic cancer
surgical exploration
folfirinox
  • 0 views
  • 19 Feb, 2024
Childhood Allergy and the Neonatal Environment

Previous birth cohort studies have found early-life environmental factors such as allergies, pollutants, viruses and bacteria have all contributed to the development of asthma and allergies. Investigators are doing this research because there continues to be a strong need to understand the root causes of asthma and allergies.

hay fever
asthma
rhinitis
allergic rhinitis
pollen allergy
  • 0 views
  • 19 Feb, 2024