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Found 4342 clinical trials
Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

This study compares gadolinium contrast-enhanced Abbreviated MRI (AMRI) to standard ultrasound for Hepatocellular Carcinoma (HCC) screening and surveillance in subjects with liver cirrhosis.

carcinoma
hepatocellular carcinoma
cirrhosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
RCT on Effect of Lymph Node Mapping by Indocyanine Green Via Submucosal or Subserosal Injection

The purpose of this study was to evaluate whether submucosal or subserous injection of indocyanine green during laparoscopic lymph node dissection of gastric cancer was different in tracing lymph nodes of gastric cancer. The patients with gastric adenocarcinoma (cT1-4a, Nmuramel +, M0) were studied.

metastasis
gastric adenocarcinoma
cancer
adenocarcinoma
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Infigratinib in Recurrent Glioblastoma Patients

Participants will be administered infigratinib prior to surgical resection of their tumor.

fgfr3 k650e
measurable disease
red blood cell transfusion
local pathology review
hair thinning
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

The primary hypothesis is that pembrolizumab + lenvatinib is superior to SOC chemotherapy with respect to ORR per modified Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by blinded independent central review.

measurable disease
solid tumour
carboplatin
cavity
paclitaxel
  • 0 views
  • 19 Feb, 2024
  • 3 locations
An N-of-1 Trial of an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain for Cancer-related Difficulties

<p>Chronic pain is a commonly occurring complication of cancer but access to the first-line recommended treatment (pain-focused cognitive behavioral therapy - CBT) is limited outside of specialist pain clinics in Sweden, and these clinics do not routinely accept people with cancer-related pain.

  • 0 views
  • 15 Jan, 2025
  • 1 location
A Study of Hydroxychloroquine vs Placebo to Prevent COVID-19 Infection in Patients Receiving Radiotherapy

The researchers are doing this study to find out whether the study drug hydroxychloroquine can prevent infection with the COVID-19 virus, compared with placebo, in people who are receiving radiation therapy for their cancer. The placebo used in this study is a tablet that looks the same as the study …

systemic therapy
SARS
acute respiratory syndrome (sars)
covid-19
pharyngitis
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma

This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent chemoradiotherapy(CCRT) combined with nimotuzumab can improve the survival rate of high-risk patients and may provide new evidence for individualized comprehensive treatment of …

egfr blocker
cancer
chemoradiotherapy
nimotuzumab
carcinoma
  • 4 views
  • 19 Feb, 2024
  • 1 location
Prehabilitation for Gastrectomy

Prehabilitation has been demonstrated to be an effective strategy to improve outcomes in patients undergoing some of the abdominal operations. It may increase the physical capacity of the patient, improve postoperative quality of life and even decrease the postoperative morbidity. Currently, the most effective strategy seems to be a trimodal …

cancer
gastric cancer
gastrectomy
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Radical Radiotherapy and Chemotherapy Combined With Maintenance Chemotherapy in the Treatment of Stage N3 NPC

This study is a randomized, phase II, prospective, multicenter clinical trial to evaluate the efficacy and safety of radical chemoradiotherapy plus oral capecitabine/teggio for 1 year in patients with N3.

chemoradiotherapy
nasopharyngeal carcinoma
alt/ast
carcinoma
capecitabine
  • 0 views
  • 19 Feb, 2024
  • 1 location
Bintrafusp Alfa in Previously Treated Patients With Recurrent and Metastatic (R/M) Non-keratinizing Nasopharyngeal Carcinoma (NPC)

This would be a phase II prospective single arm mono-institutional study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of bintrafusp alfa in previously treated patients with recurrent and metastatic (R/M) non-keratinizing nasopharyngeal carcinoma (NPC).

metastasis
measurable disease
platelet count
adjuvant
neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 1 location