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Found 79 clinical trials
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

They will have repeats of the screening tests. They will also have 2 skin biopsies. These will be from both lesions and unaffected areas. The areas will be injected with a numbing medicine. A round cutting device will remove small pieces of skin from each area.

vitamins
body mass index
urine test
chronic inflammation
nicotinamide riboside
  • 0 views
  • 19 Feb, 2024
Full Metall Jacket Multilevel Segment

Hypothesis: "Total" endovascular revascularization of a multistory lesion of the iliac-femoral-popliteal segment is safer and a better quality of life is achieved in comparison with hybrid intervention. The lack of damage to the skin avoids complications in the postoperative and remote periods of observation, thereby improving the quality of life

  • 0 views
  • 19 Feb, 2024
HidraWear AX HS Study

The product, HidraWear AX is and adhesive free wound dressing system for the every day home care of Hidradenitis Suppurativa (HS), a debilitating disease of the skin for which there are limited wound dressing products. This is a study to assess the use HidraWear Ax vs current product and method …

hidradenitis
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  • 19 Feb, 2024
Post Market Usability Evaluation Of The PicoSure Pro Device

The intended use of the PicoSure and PicoSure Pro devices used in this study is to treat additional patients with the new PicoSure Pro device and collect additional data on the devices.

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  • 19 Feb, 2024
Physiological Changes Induced Through MEP Conditioning in People With SCI

Research participants will be asked to stand, sit, and walk during the study sessions. Electrodes are placed on the skin over leg muscles for monitoring muscle activity. For examining brain-to-muscle connections, the study team will use transcranial magnetic stimulation.

traumatic brain injury
discomfort
spinal cord injury
nervous
spinal cord disorder
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  • 19 Feb, 2024
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

platinum-based chemotherapy
vascular endothelial growth factor
growth factor
advanced melanoma
cancers, ovarian
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  • 19 Feb, 2024
A Study to Look at How Safe NNC0472-0147 is in Healthy People and in People With Type 2 Diabetes

Participants will get once daily injections of either NNC0472-0147 or insulin glargine for a treatment period of fourteen days. The injections will be given under the skin (subcutaneously, s.c.) of the left thigh. Participants will be in the study for about 7 weeks. There will be 15 visits with the …

diabetes
low density lipoprotein
cholesterol level
type 1 diabetes mellitus
insulin
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  • 19 Feb, 2024
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

This study will investigate the effects of atezolizumab on select cancer types in people whose analysis of tumour DNA and RNA indicates they may be sensitive to atezolizumab. This study aims to determine if the information from the cancer genome analysis corresponds with the effects of atezolizumab on individuals and …

metastatic cancer
solid tumour
international normalised ratio
platelet count
international normalized ratio (inr)
  • 0 views
  • 19 Feb, 2024
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

biologic therapy
biotherapy
pediatric
corticosteroids
trastuzumab
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  • 19 Feb, 2024
The Anti-inflammatory Effects of Hark ny Medicinal Water

The study aims to provide evidence on the effectiveness of Harkny medicinal water in psoriatic and rheumatoid arthritis patients using subjective and objective methods. It is a cross-over study, so first half of patients will receive medicinal water, the other half will receive tap water treatment, and after 6 months …

renal disease
skin lesion
psoriasis
psoriasis vulgaris
arthritis
  • 0 views
  • 19 Feb, 2024