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Found 47 clinical trials
Diagnostic Performance of a New Method for the Echocardiographic Assessment of Coronary Arteries Abnormalities

Coronary artery anomalies (CAA) are a rare congenital condition, accounting abnormalities of origin, course, destination, size, and number of the coronary vessels. In normal hearts, the coronary arteries, the left and right coronary arteries (LCA and RCA, respectively) originate from the two facing aortic sinuses of Valsalva, so-called left and …

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  • 19 Feb, 2024
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants

This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.

social interactions
diabetes
social interaction
lung disease
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  • 19 Feb, 2024
Incidence of Rhinological Morbidities During Endonasal Pituitary Surgery With or Without Nasoseptal Flap

Determine and compare prospectively the incidence of rhinological adverse events during pituitary surgery with or without nasoseptal flap

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  • 19 Feb, 2024
Clinical and Functional Outcomes 2 Years After ACL Repair and InternalBrace Ligament Augmentation in Comparison With ACL Reconstruction

The aim of this study is to assess the clinical, biomechanical and functional outcome 2 years after anterior cruciate ligament (ACL) repair and InternalBraceTM augmentation now in direct comparison to ACL reconstruction and to identify potential deficits compared to the contralateral healthy side as well as with a knee-healthy age-matched …

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  • 19 Feb, 2024
Direct Effect of Caffeine on Diaphragmatic Muscles

Right and left sides of diaphragm thickness are being measured by two clinicians on B mode ultrasound by anterior subcostal view. The velocity before and after caffeine administration will be calculated, dividing excursion frequency (parameter) for inspiratory time.

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  • 19 Feb, 2024
The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy

The study focuses on the development of a new personalized approach to diagnostics and surgical treatment of patients with ischemic cardiomyopathy. The algorithm for selection of patients for certain type of cardiac surgery will be developed. The models for prediction of the risks and outcomes of cardiac surgery will be …

heart surgery
coronary bypass
infarct
stenosis
coronary artery bypass graft
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  • 19 Feb, 2024
Role of Nasal Dysbiosis in Parkinson Disease

Olfactory dysfunction is frequent in Parkinson Disease (PD) and may be present years before the motor symptoms appear. The early olfactory dysfunction could result from environmental factors acting through the nasal cavity such as microbial communities. In across-sectional bicentric study, groups of 160 PD patients and 160 controls will be …

motor symptoms
cognitive deficit
deficit
parkinson's disease
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  • 19 Feb, 2024
Rheumatology Patient Registry and Biorepository

To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.

connective tissue disease
giant cell arteritis
polymyositis
antiphospholipid syndrome
scleroderma
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  • 19 Feb, 2024
Dresden Corneal Disease and Treatment Study

The purpose of this study is long-term follow up of patients with corneal diseases to analyze the quality of surgical interventions and diagnosis. Corneal ectasia, especially keratoconus, is a corneal disease that leads to an irreversible loss of visual acuity while the cornea becomes steeper, thinner and irregular. For these …

corneal diseases
corneal ectasia
keratoconus
corneal topography
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  • 19 Feb, 2024
Predictors of Better Outcomes After Severe Acquired Brain Injuries

Severe Acquired Brain Injury is defined as a traumatic, post-anoxic, vascular or other brain damage that causes coma for at least 24 hours and leads to permanent disability with sensorial, motor, cognitive or compartmental impairment. In this context, an accurate characterization of individual patients' profile in terms of neuronal damage, …

coma
bdnf
traumatic brain injury
perinatal brain injury
genetic analysis
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  • 19 Feb, 2024