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Found 4342 clinical trials
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

solid tumour
squamous cell carcinoma
cervical cancer
ovarian ca
small cell lung cancer
  • 0 views
  • 19 Feb, 2024
  • 3 locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers.

lymphoma
venetoclax
pembrolizumab
growth factor
drug test
  • 0 views
  • 19 Feb, 2024
  • 39 locations
Altered Tumor Oxygenation by Metformin a Potential Step in Overcoming Radiotherapy Resistance in LACC

Poor tumor oxygenation (hypoxia) is an established negative prognostic and predictive factor in locally advanced cervical cancer (LACC). Hypoxia-modifying measures implemented in the clinic are lacking.

metformin
cervical neoplasm
cisplatin
hypoxia
renal function
  • 0 views
  • 19 Feb, 2024
  • 1 location
RISI in the Treatment of Recurrent Metastatic SCC of Thoracic Inlet Lymph Nodes

The malignant tumor at the thoracic entrance is difficult to be surgically removed, and radiotherapy or radiotherapy based comprehensive treatment is often chosen at the initial diagnosis.

anticoagulants
coagulopathy
squamous cell carcinoma
metastatic squamous cell carcinoma
solid tumors
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

Lenvatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

anticoagulants
beta human chorionic gonadotrophin
kidney cancer stage iii
pembrolizumab
chorionic gonadotropin
  • 8 views
  • 19 Feb, 2024
  • 1 location
A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET

A Phase II trial aiming to assess the safety and activity of the combination of cabozantinib plus lanreotide in gastroenteropancreatic (GEP) and thoracic neuroendocrine tumor (NET): The LOLA trial

coronary artery bypass graft surgery
renal function
arterial dissections
congestive heart failure
skin cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

This is a phase 1/2 multicenter, multi-regional, open-label, first-in-human study of IBI3014 in participants with unresectable locally advanced or metastatic solid tumors.

  • 0 views
  • 22 Aug, 2025
  • 2 locations
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

cancer
squamous cell carcinoma
recurrent head and neck squamous cell carcinoma
head and neck cancer
cancer of the head
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

cancer
pembrolizumab
exhausted
gene amplification
gastric tumor
  • 0 views
  • 19 Feb, 2024
  • 7 locations
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

solid tumour
human chorionic gonadotropin
hair thinning
health screening
her2/neu-negative breast cancer
  • 0 views
  • 19 Feb, 2024
  • 5 locations