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Found 4335 clinical trials
Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers RT-CAMSS Study

This trial tests new methods and materials for the real-time chemotherapy-associated side effects monitoring support system (RT-CAMSS) in patients with gastrointestinal cancers undergoing chemotherapy. RT-CAMSS is a monitoring support system that provides patients with evidence-based information and side-effect management and coping skills, emotional support and validation, and proactive care via …

stage iiib colorectal cancer ajcc v8
fluorouracil
adenocarcinoma
squamous cell carcinoma
docetaxel
  • 0 views
  • 24 Nov, 2025
  • 1 location
Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

The investigators propose a phase II randomized-controlled study on using durvalumab in combination with induction chemotherapy followed by concurrent chemoradiation and adjuvant durvalumab, compared to induction chemotherapy followed by concurrent chemoradiation for previously untreated locoregionally advanced stage III to IVA NPC. In parallel, the investigators will also perform collateral tumor …

bilateral salpingectomy
corticosteroids
gemcitabine
durvalumab
prednisone
  • 0 views
  • 19 Feb, 2024
  • 1 location
EBRT and HDR Brachytherapy for Unfavorable-intermediate High and Very High-risk Prostate Cancer

This study is trying to find out if the combination of Androgen deprivation therapy (ADT), MRI guided high dose radiation (HDR) brachytherapy treatment (internal radiation implant procedure) and external beam radiation therapy (EBRT) treatments lead to less side effects. This study is also looking at patient outcomes, quality of life, …

adenocarcinoma
androgen suppression
androgens
prostate adenocarcinoma
brachytherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cisplatin+Pembrolizumab+RT in Vulvar Cancer

This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma. This research study involves the following: Cisplatin (standard of care drug) Pembrolizumab (investigational drug) Radiation Therapy (standard of care intervention)

anticoagulant therapy
international normalized ratio (inr)
primary tumor
squamous cell carcinoma of the vulva
pediatric
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer

In this research study, is assessing the feasibility of using an MR-guided implantable microdevice to measure tumor response to chemotherapy and other clinically relevant drugs in participants that have prostate cancer and are scheduled for a radical prostatectomy.

carcinoma
neutrophil count
prostatectomy
  • 2 views
  • 19 Feb, 2024
  • 1 location
A Study of CT-RD06 Cell Injection in Patients With Relapsed or Refractory CD19+ B-cell Hematological Malignancy

A study of CT-RD06 cell injection in patients with relapsed or refractory CD19+ B-cell hematological malignancy.

ejection fraction
lymphoblastic leukemia
lymphoid leukemia
chemotherapy regimen
leukemia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

hras gene
metastases
anticonvulsants
nervous system
blood transfusion
  • 0 views
  • 19 Feb, 2024
  • 83 locations
Irreversible Electroporation of Unresectable Liver Tumors

The aim of this study is to evaluate the safety and feasibility of curative intended irreversible electroporation (IRE) in the treatment of liver tumors neighboring major vessels or bile ducts.

liver tumor
hepatoma
irreversible electroporation
metastasis
biliary tract cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

This trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

non-small cell lung cancer
stage ia1 lung cancer ajcc v8
lung cancer
non-small cell carcinoma
cancer
  • 0 views
  • 19 Feb, 2024
  • 22 locations
A Study of CTA101 UCAR-T Cell Injection in Patients With Relapsed or Refractory CD19+ B-line Hematological Malignancy

A study of CTA101 UCAR-T cell injection in patients with relapsed or refractory CD19+ B-line hematological malignancy

ejection fraction
remission
lymphoblastic leukemia
lymphoid leukemia
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location