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Found 1297 clinical trials
Engaging Adolescents in Decisions About Return of Genomic Research Results

Recent recommendations to return children's results for adult-onset conditions to parents anytime whole exome or genome sequencing is performed, as well as growing expectations to return research results to participants on a large-scale basis, mean adolescents will increasingly be engaged in assenting (<age 18) and consenting (>age 18) to return …

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  • 19 Feb, 2024
The Effect of a Predictive Model of Bowel Preparation Based on Procedure-related Factors

If patients with inadequate bowel preparation were identified before the procedure, enhanced strategy could be offered to achieve better bowel cleaning. Currently, there were three predicting models of inadequate bowel preparation established based on patient-related factors.

bowel preparation
  • 0 views
  • 19 Feb, 2024
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]).

platinum-based chemotherapy
non-small cell lung cancer
stage iv non-small cell lung cancer
immune checkpoint inhibitor
non-squamous non-small cell lung cancer
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  • 19 Feb, 2024
  • 169 locations
Role of Lymphnode Dissection in Men With Prostate Cancer Treated With Radical Prostatectomy

In case of lymph node metastasis, depending on the number of affected lymph nodes, an adjuvant radiation with or without additional hormone therapy may be discussed in order to stop or delay further progression of the disease. Since the procedure carries additional risks, it is controversial.

immunological adjuvant
endocrine therapy
prostatectomy
lymph node metastases
metastasis
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  • 19 Feb, 2024
Randomised Evaluation of COVID-19 Therapy

RECOVERY is a randomised trial investigating whether treatment with either Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Convalescent plasma or Tocilizumab prevents death in patients with COVID-19.

lopinavir
ritonavir
immunoglobulins
immunoglobulin
covid-19
  • 0 views
  • 19 Feb, 2024
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

cardiac arrest
resuscitation
coma
induced hypothermia
life support
  • 0 views
  • 19 Feb, 2024
  • 1 location
Identification of Fatty Liver With Advanced Fibrosis in Type 2 Diabetes Using Simple Fibrosis Scores and Electronic Reminder Messages

Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide and is a major cause of cirrhosis and liver cancer in Western countries. Because of its close association with obesity and diabetes, most patients are seen by primary care physicians and endocrinologists rather than hepatologists. Previous …

fatty liver
nash
diabetes
fibrosis
cirrhosis
  • 0 views
  • 19 Feb, 2024
Remote Exercise SWEDEHEART Study

This study evaluates if remote video exercise-based cardiac rehabilitation (exCR), offered as an alternative to centre-based exCR, can increase the proportion of patients post myocardial infarction (MI) successfully completing an exCR-program.

acute myocardial infarction
infarct
cardiac rehabilitation
myocardial infarction
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  • 19 Feb, 2024
Evaluation of Thiw he Gluw 'Akapi Substance Use Prevention Program

Researchers at the Centers for American Indian and Alaska Native Health in the Colorado School of Public Health at the University of Colorado completed an intensive community-engaged process to rigorously adapt the Strengthening Families Program for Parents and Youth 10-14 for the cultural context of a Northern Plains reservation community, …

suicide
substance use
substance use prevention
drug abuse
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  • 19 Feb, 2024
Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus

Aim To investigate the effect of sentinel lymph node (SLN) sampling on the prognosis of patients with middle-high risk endometrial cancer obviously confined to the uterus before surgery.

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  • 19 Feb, 2024