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Found 365 clinical trials
Concordance of the IHC4 Score Performed in Local or Central Laboratory to Endopredict in ER+/HER2- Breast Cancer

Retrospective observational, multicentric study assessing the immunohistochemistry (IHC) based test IHC4 score in infiltrating early breast cancer: comparison of the score performed in local laboratory vs in a central laboratory and concordance with a molecular gold standard classifier (EndoPredict).

invasive breast cancer
er-positive breast cancer
HER2
immunohistochemistry
ffpe
  • 0 views
  • 19 Feb, 2024
  • 1 location
Endometrial Cancer Conservative Treatment (E.C.Co). A Multicentre Archive

Approximately one fourth of cases of endometrial cancer (EC) are diagnosed in premenopausal women, of whom approximately 40% wish to preserve their fertility. When arising in young women, EC usually presents with favorable prognostic features, as a focal, well differentiated endometrioid tumor, with minimal or absent myometrial invasion. This profile …

laparoscopy
endometrial cancer
progestin
lymphadenectomy
oophorectomy
  • 0 views
  • 19 Feb, 2024
  • 19 locations
PIVKA-II for Predicting Portal Vein Thrombosis in Hepatocellular Carcinoma

The goal of this cross-sectional observational study is to evaluate the relation between Prothrombin induced by vitamin K absence II (PIVKA-II) and the presence of portal vein tumor thrombosis (PVTT) in hepatocellular carcinoma (HCC) patients.Researchers will compare PIVKA-II serum levels in HCC patients with PVTT and without PVTT.Participants will undergo …

  • 0 views
  • 08 May, 2025
MPA AUC Monitoring in Patients Receiving MMF for Diffuse Cutaneous or Pulmonary Involvement in Systemic Sclerosis

To define a target value of AUC MPA to improve the modified Rodnan score and / or respiratory impairment (DLCO or FVC) at one year in patients receiving MMF for the treatment of diffuse cutaneous or interstitial lung damage of systemic sclerosis.

progressive systemic sclerosis
chest x-ray
cyclophosphamide
raynaud's syndrome
corticosteroids
  • 0 views
  • 19 Feb, 2024
  • 1 location
Early Detection of Familial Hypercholesterolemia in Children

Heterozigous FH is an underdiagnosed disease in the paediatric population. Its early detection, would allow us to initiate lifestyle therapeutical changes and early pharmacological therapy if necessary. This is a key fact to reduce atherosclerosis progression and cardiovascular risk in adulthood. Moreover, it will allow, detecting the first and second …

early detection
genetic disorder
nephrotic syndrome
diabetes
atherosclerosis
  • 0 views
  • 19 Feb, 2024
  • 2 locations