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Found 1061 clinical trials
A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants

The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants.

radiopharmaceuticals
  • 0 views
  • 19 Feb, 2024
  • 1 location
Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial

The purpose for this study is to determine whether left posterior wall isolation (PWI) in addition to pulmonary vein isolation (PVI) is effective as ablation strategy for persistent atrial fibrillation (AF).

antiarrhythmic drug
atrial fibrillation
pulmonary vein isolation
conversion to sinus rhythm
persistent atrial fibrillation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Characterisation of the Nasal Microbiome in Patients With N-ERD

Here, the investigators plan to analyse the nasal microbiome in these patients and to compare it to nasal samples from CRSwNP and CRSsNP patients as well as healthy controls (in total 80 subjects). This will provide insights into potential differences in the microbiome as compared to other CRS patients and …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Wells and Enteric Disease Transmission Trial (WET - Trial)

These cases of GI can cause a significant burden in terms of health care costs and lost work/school days, as well as increased risk to developing longer term health complications. This impact is magnified when accounting for vulnerable populations such as children under the age of 5, the elderly and …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma

This study aims to collect convalescent plasma and use it as experimental treatment in critically ill Covid-19 patients in order to reduce mortality and length of stay in intensive care unit.

organ failure
critical illness
acute respiratory distress
covid-19
shock
  • 0 views
  • 19 Feb, 2024
  • 1 location
Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture

The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo

hip fracture
ropivacaine
delirium
ache
  • 0 views
  • 19 Feb, 2024
  • 1 location
Tofacitinib for Immune Skin Conditions in Down Syndrome

Investigators will also measure the impact of interferon inhibition on a variety of molecular markers, as well as the cognitive abilities and quality of life of participants.

antibiotics
atopic diathesis
unbalanced translocation of chromosome
herpes zoster
psoriasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Hyperpolarized Imaging for New Treatments

The introduction of triple combination CFTR modulator therapy for patients with Cystic Fibrosis (CF) with at least one copy of the deltaF508 mutation is expected to provide major health benefits, but will also require novel outcome measures that can detect CF lung disease at an early stage, capture the efficacy …

fibrosis
antibiotics
pulmonary disease
pilocarpine
cystic fibrosis transmembrane conductance regulator
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Early Versus Late Administration of Insulin Glargine in T1DM During Fasting Ramadan

To compare different timing of insulin Glargine administration (early-6 pm versus standard bedtime-10 pm) as part of standard of care in patients with type1 diabetes who wish to fast the month of Ramadan.

insulin injection
insulin
  • 0 views
  • 19 Feb, 2024
  • 1 location
Spacer Graft Study (abc)

To determine which of three types of spacer grafts (hard palate vs autologous ear cartilage vs Enduragen) are the most effective in lower eyelid retraction repair outcomes as measured by MRD2 (margin to reflex distance 2)

Accepts healthy volunteers
  • 0 views
  • 14 May, 2025
  • 1 location