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Found 656 clinical trials
Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities

This phase I/II trial studies the side effects and best dose of cabozantinib when given with radiation therapy and how well it works in treating patients with sarcoma of the extremities. Cabozantinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving …

serum pregnancy test
g-csf
cancer
oral contraceptives
primary tumor
  • 0 views
  • 19 Feb, 2024
Patient-Derived Organoids for Rectal Cancer

The purpose of this study is to determine the feasibility of establishing patient-derived organoids from pre-treatment rectal adenocarcinoma biopsies.

proctoscopy
rectal cancer
adenocarcinoma of rectum
cancer
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

Participating in the program may improve knowledge and confidence about follow-up care, communication with cancer care and primary care doctors, and quality of life after cancer treatment in non-small cell lung cancer or colorectal cancer survivors.

stage ia1 lung cancer ajcc v8
stage ia2 lung cancer ajcc v8
stage iii colorectal cancer ajcc v8
stage ib lung cancer ajcc v8
stage i colorectal cancer ajcc v8
  • 4 views
  • 19 Feb, 2024
Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer

The study researchers will use computers to analyze the combined results of the imaging tests and the genetic and immune system tests on the tumor samples. The study researchers think that this information will help them more accurately predict the way tumors respond to treatment, which may improve their ability …

ovarian carcinoma
carcinoma
cancer
ovarian cancer
  • 0 views
  • 19 Feb, 2024
Neo-TACE-HAIC for BCLC B Stage HCC (Neoconcept)

Pilot study showed TACE combined HAIC (TACE-HAIC) had better tumor response, with low progression disease rate. Whether TACE-HAIC would improve survival for patients with BCLC B stage is need to further to study.

fluorouracil
TACE
oxaliplatin
folfox regimen
hepatocellular carcinoma
  • 0 views
  • 19 Feb, 2024
HCC Surveillance: Comparison of Abbreviated Non-contrast MRI and Ultrasound Surveillance in Cirrhotic Patients With Suboptimal Ultrasound Visualisation

All international guidelines recommend 6-monthly ultrasound surveillance for patients at risk for liver cancer (hepatocellular carcinoma or HCC), such as patients with cirrhosis. The aim of surveillance is to detect HCC at an early stage when it is still potentially curable.

fibroscan
hepatocellular carcinoma
carcinoma
liver disease
cancer
  • 0 views
  • 19 Feb, 2024
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma

This trial is a multi-center, phase III, randomized (1:1) clinical trial. The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.

radiofrequency ablation
stereotactic body radiation therapy
hepatocellular carcinoma
carcinoma
recurrent hepatocellular carcinoma
  • 0 views
  • 19 Feb, 2024
Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection

This trial is a randomized, double-blind, multinational Phase III study to evaluate the efficacy and safety of preemptive treatment with FTD/TPI compared with administration of placebo as follow-up, which is the standard of care, in patients who underwent curative resection of colorectal cancer and then tested positive for ctDNA.

trifluridine/tipiracil
platelet count
adenocarcinoma
colorectal cancer
metastasis
  • 0 views
  • 19 Feb, 2024
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

This phase II trial studies how well acalabrutinib, lenalidomide, and rituximab work in treating patients with CD20 positive stage III-IV, grade 1-3a follicular lymphoma. Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work …

grade 2 follicular lymphoma
aptt
lenalidomide
revlimid
international normalized ratio
  • 0 views
  • 19 Feb, 2024
B002 in Patients With HER2-positive Breast Cancer

To assess the safety and tolerability characteristics of B002 in patients with HER2-positive recurrent or metastatic breast cancer. The dose-limiting toxicity (DLT) was assessed and the maximum tolerated dose (MTD) was explored.

bilateral breast cancer
her2-positive breast cancer
monoclonal antibodies
cancer
monoclonal antibody therapy
  • 0 views
  • 19 Feb, 2024