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Found 1304 clinical trials
Lap-assisted vs. US-Guided Visualization of TAP Blocks

Peripheral nerve blocks have been effective in decreasing post-operative pain as well as the use of narcotics for numerous years. Typically, these blocks are placed by anesthesiologist via ultrasound. In more recent years, surgeons have been placing nerve blocks laparoscopically. Since there are few studies that looks compare the two …

laparoscopic surgery
nerve blocks
peripheral nerve block
nerve block
narcotics
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  • 19 Feb, 2024
Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers

This is a non-randomised study to develop personalised treatment approaches in participants with Locally Advanced Head and Neck Cancer (HNC) of the oropharynx and base of skull by integrating the use of MR-guided Adaptive Radiotherapy (MRgRT) and functional image-guided radiotherapy (FIgRT). The study is made up of two parts: Feasibility …

squamous cell carcinoma of head and neck
carcinoma
cancer
platinum-based chemotherapy
neck cancer
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  • 19 Feb, 2024
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

root canal
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  • 19 Feb, 2024
Prophylactic Muscle Flaps in Vascular Surgery

Previous studies have suggested that prophylactic muscle coverage in high-risk patients undergoing revascularization procedures through a groin incision have the potential to reduce rates of complications and re-operation. This is a prospective randomized control trial to test this hypothesis at the University of Wisconsin Hospitals and Clinics.

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  • 19 Feb, 2024
Fiber Metabolism in Chronic Obstructive Pulmonary Disease

The impact of fiber intake on short chain fatty acid (SCFA) metabolism has not been studied in subjects suffering from COPD. The purpose of this study is to compare changes in SCFA metabolism after inulin vs. placebo intake in COPD patients to healthy matched controls. This protocol is an extension …

pulmonary disease
lung disorder
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  • 19 Feb, 2024
PTX-35 in Patients With Advanced Solid Tumors

A Phase I, First-in-Human, Dose-Escalation Study to Evaluate the Safety of the Monoclonal Antibody PTX-35 in Patients with Advanced Solid Tumors Refractory to Standard of Care

unresectable solid tumor
liver metastasis
solid tumour
antibody therapy
metastasis
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  • 19 Feb, 2024
Evaluation of Hydration Status When Consuming Alkaline Water Compared to Reverse Osmosis Purified Water.

To conduct a randomized, double-blinded, placebo-controlled, cross-over trial in a population of chronically, moderately dehydrated people comparing two waters on hydration status.

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  • 19 Feb, 2024
FISH in Diagnosis of Biliary Stricture

The management of biliary strictures depends on their correct pre-operative evaluation which remains challenging. Despite the emerging multitudes of new diagnostic opportunitiesmodalities we have today, there is still a large number of biliary stenosis misdiagnosed with a profound negative impact on the patients outcome. The study aims to proove the …

pre-operative evaluation
stenosis
endoscopic retrograde cholangiopancreatography
tissue sampling
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  • 19 Feb, 2024
Telemedicine Follow-up for Post-ACS Patients

The aim is to compare the safety of using telemedicine and office visit follow-up in post-acute coronary syndrome patients

acute coronary syndrome
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  • 19 Feb, 2024
Preschool ADHD On-line Behavioral Treatment

The primary goal of the proposed project is to test the feasibility of parent and teacher/childcare providers use of the ADHD web portal-integrated behavioral treatment modules with preschool children with ADHD in order to improve the access to and the integrity of evidence-based behavioral treatment strategies for young children with …

attention deficit hyperactivity disorder
behavior modification
impulsive behavior
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  • 19 Feb, 2024