Found 1297 clinical trials
SGLT2 Inhibition in Older Obese Adults With Pre-diabetes
Inhibitors of the sodium-glucose co-transporter (SGLT2) are FDA-approved for the treatment of type 2 diabetes (T2DM). Their mechanism of action involves lowering of blood glucose concentration secondary to increased glucose excretion of glucose by the kidney. These drugs also improve body weight, blood pressure, and cardiac function. Based on these …
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- 19 Feb, 2024
A Study to Assess the Effect of Fluvoxamine and Smoking on Pharmacokinetics ( the Movement of Drugs Within the Body) of AZD4635 in Healthy Volunteers
This study is a Phase I, open-label, non-randomized, 2-period, fixed-sequence study in healthy volunteers who are either smokers or non-smokers, performed at a single Clinical Unit.
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- 19 Feb, 2024
A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors
This is an open label Phase 1, First in Human trial of TST001, a recombinant humanized anti-Claudin 18.2 (CLDN18.2) IgG1 monoclonal antibody. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic, colon and lung cancers.
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- 19 Feb, 2024
Head Position on Preventing Emergence Cough
The purpose of this study is to investigate the effect of head position on prevent the emergence cough followed by endotracheal extubation.
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- 19 Feb, 2024
Gas Tamponade for Prevention of Postoperative Vitreous Hemorrhage in Diabetics
Subjects undergo vitreous substitution with either SF6 gas or fluid during vitrectomy.
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- 19 Feb, 2024
Primary Percutaneous Pericardiotomy for Malignant Pericardial Effusion (PMAP)
Pericardial effusion is a common complication in patients with metastatic malignancy. While pericardiocentesis provide effective relieve from life-threatening situation such as cardiac tamponade, recurrence of pericardial effusion after pericardiocentesis is common. We hypothesize that percutaneous balloon pericardiotomy in addition to standard pericardiocentesis with prolonged drainage can prevent pericardial effusion recurrence …
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- 19 Feb, 2024
The Effectiveness of a Recovery Program for People With Mental Illness: A Multicenter Study
Recovery-oriented approach has been the main trend in mental health field. However, few recovery-oriented programs are available in Taiwan, and many Taiwaneses with mental illness don't understand the concepts of recovery. A program which provides recovery knowledge and assists in setting recovery goals is beneficial for Taiwaneses with mental illness. …
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- 19 Feb, 2024
Evaluation of an Ostomy Leakage Detection System
This study will evaluate the safety and efficacy of an ostomy leakage detection system.
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- 12 Aug, 2024
Non-invasive Lipolysis on Human Thighs and Saddlebags
The study is a prospective two-arm, open-label, interventional study with four treatment procedures and two follow-up visits.
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- 19 Feb, 2024
Lap-assisted vs. US-Guided Visualization of TAP Blocks
Peripheral nerve blocks have been effective in decreasing post-operative pain as well as the use of narcotics for numerous years. Typically, these blocks are placed by anesthesiologist via ultrasound. In more recent years, surgeons have been placing nerve blocks laparoscopically. Since there are few studies that looks compare the two …
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- 19 Feb, 2024