Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 33 clinical trials
Satisfaction Survey on PINS Stimulator System for Patients With Parkinson's Disease

This study will be done because the investigators would like to evaluate product satisfaction of two PINS products (product A, product B) that are to evaluate the effectiveness of rechargeable and non-rechargeable Deep Brain Stimulation (at baseline visit and at follow-up visit) and by evaluating their responses to the product …

brain stimulation
parkinson's disease
  • 622 views
  • 19 Feb, 2024
  • 1 location
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

methyldopa
muscle rigidity
resting tremor
alpha-synuclein
parkinson's disease
  • 0 views
  • 19 Feb, 2024
Neurodegenerative Diseases Registry

Due to the overlapping presentation and similar brain pathology, especially in the early stage of the diseases, it is difficult to differentiate idiopathic Parkinson's disease (iPD) from atypical parkinsonian syndromes, such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP).

neurodegenerative disorder
motor neuron disease
supranuclear palsy
vascular dementia
drug trials
  • 0 views
  • 19 Feb, 2024
Biological Sample Collection for Research and Biobanking

The New York Stem Cell Foundation (NYSCF) is performing this research to study different conditions and diseases by using cells from the body (such as skin or blood cells). NYSCF uses these samples to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, …

genetic testing
  • 0 views
  • 19 Feb, 2024
Diagnosis of Parkinson s Disease by Means of Submandibular Gland Needle Biopsy

This study includes 35 PD patients who underwent submandibular gland needle biopsy. 25 neurologically healthy patients of the local otolaryngological clinic, in whom submandibular gland needle biopsy was performed due to a clinical indication, serve as controls.

parkinson's disease
  • 0 views
  • 19 Feb, 2024
Antigen Presentation and Lymphocyte Response in Parkinson's Disease  

The way the immune system responds to certain PD-related proteins in PD donors compared to the way it responds in persons without or fewer PD related proteins is not well studied and this study aims to analyze the autoimmune response in each group. The study involves a one time visit …

bradykinesia
muscle rigidity
tremor
resting tremor
parkinson's disease
  • 1784 views
  • 19 Feb, 2024
  • 3 locations
Deep Brain Stimulation (DBS) for Parkinson's Disease International Study  

To gather data on DBS Therapy effectiveness in different geographic populations.

dyskinesia
brain stimulation
parkinson's disease
levodopa
  • 6 views
  • 19 Feb, 2024
  • 15 locations
Attentional Performance in Parkinson Disease

Background Parkinson Disease (PD) is a nervous system disorder that affects movement. Dopamine is an important neurotransmitter in the brain. As PD progresses, there is less and less dopamine in the brain.

attention deficit
nervousness
parkinsonism
nervous system disorder
parkinson's disease
  • 0 views
  • 19 Feb, 2024
Role of Nasal Dysbiosis in Parkinson Disease

Olfactory dysfunction is frequent in Parkinson Disease (PD) and may be present years before the motor symptoms appear. The early olfactory dysfunction could result from environmental factors acting through the nasal cavity such as microbial communities.

deficit
motor symptoms
parkinson's disease
cognitive deficit
  • 0 views
  • 19 Feb, 2024
LRRK2 G2385R Leucocyte and Urine Biomarker Study

Given the emerging evidence on LRRK2-related biomarkers, this project will focus on identifying leucocyte and urine biomarkers that are altered by the LRRK2 G2385R variant, and investigating the effects of LRRK2 kinase inhibitor (MLi-2) on these biomarkers, using immunoblotting and mass spectrometry.

movement disorder
parkinson's disease
  • 0 views
  • 19 Feb, 2024