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Found 102 clinical trials
SGLT2 Inhibition in Older Obese Adults With Pre-diabetes

Inhibitors of the sodium-glucose co-transporter (SGLT2) are FDA-approved for the treatment of type 2 diabetes (T2DM). Their mechanism of action involves lowering of blood glucose concentration secondary to increased glucose excretion of glucose by the kidney.

hba1c
oral glucose tolerance test
hemoglobin a1c
blood sugar
sglt2
  • 0 views
  • 19 Feb, 2024
Scripps Digital Diabetes: Cloud-Based Continuous Glucose Monitoring (CB CGM)

The work proposed pushes the limits of these challenges by providing evidence, identified by a team-based approach to glucose management in an underserved and understudied population supplementing prior data designed to improve outcomes among high-risk patients with type 2 diabetes (T2D) and related cardio metabolic conditions. The proposed intervention is …

continuous glucose monitoring
cardiovascular complication
poor glycaemic control
hyperglycemia
hypoglycemia
  • 0 views
  • 19 Feb, 2024
At-Risk for Type 1 Diabetes Extension Study

This study is an extension of the NIH-sponsored AT-Risk (TN-10) type 1 diabetes study (NCT 01030861). Teplizumab-treated and placebo-treated participants in the NIH trial who develop clinical type 1 diabetes after the conclusion of that trial, are eligible to enroll and receive teplizumab treatment within one year of diagnosis of …

type 1 diabetes mellitus
teplizumab
diabetes
  • 0 views
  • 19 Feb, 2024
Injections of Glutamic Acid Decarboxylase (GAD) for LADA Type of Diabetes

This study will evaluate the effects of 3 intra-nodal injections of GAD-alum (Diamyd), together with oral vitamin D supplementation. Safety and feasibility of the treatment will be evaluated and also effects on the immune system and on the preservation of endogenous insulin production.

vitamin d
diabetes
metformin
vitamins
ergocalciferol
  • 0 views
  • 19 Feb, 2024
Incidence of Diabetes and Metabolic Disorders After TIPS in Cirrhotic Patients

Based on our retrospective data, TIPS induces in 30% of cirrhotic patients metabolic disorders associated with diabetes or pre-diabetes. The main objective is to measure the cumulative incidence of diabetes and pre-diabetes 6 months after TIPS insertion.

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  • 19 Feb, 2024
Trial - Prescreener Validate (Test)  

Trial - Prescreener Validate

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  • 19 Dec, 2024
  • 1 location
Customer Outcomes & Value Experiencing A New Monitoring Technology

To investigate whether novel insight features in new Blood Glucose Monitoring System (BGMs) can improve glycemic control.

type 1 diabetes mellitus
type 2 diabetes mellitus
blood glucose monitoring
niddm
self-monitoring of blood glucose
  • 0 views
  • 19 Feb, 2024
Cardiometabolic Effects of Rapid Glucose Excursion

The effects of rapid glucose excursions, induced by intravenous bolus application of glucose in healthy probands, on cardiometabolic and inflammatory parameters will be investigated

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  • 19 Feb, 2024
Metformin for Abdominal Aortic Aneurysm Growth Inhibition

A multi-centre population-based open-label randomized controlled trial with allocation concealment and blinded outcome assessment will examine if up to 2g metformin daily slows AAA growth in patients with small AAAs who do not have diabetes.

metformin
diabetes
abdominal aortic aneurysm
aaas
aneurysm
  • 0 views
  • 19 Feb, 2024
The Restoration of Endodontically Treated Teeth Using Indirect Full Coverage Restorations Compared to Direct Composite Resin Restorations

The use of full cuspal coverage restoration for the management root treated teeth was advocated by many clinical studies and supported by systematic reviews. However, most of the studies did not take into account the amount of tooth structure remaining before providing cuspal coverage. The strength and fracture resistance of …

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  • 19 Feb, 2024