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Found 24 clinical trials
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

This clinical trial is studying two immunotherapy drugs (nivolumab and ipilimumab) given together as a possible treatment for INI1-negative tumors.

epithelioid sarcoma
sarcoma
serum lipase
measurable disease
myelosuppressive chemotherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

A Phase1/2a Study of Rigosertib plus Nivolumab in Stage IV Lung Adenocarcinoma Patients with KRAS Mutation who Progressed on First-Line Treatment

measurable disease
stage iv lung adenocarcinoma
lung adenocarcinoma
platinum doublet
core needle biopsy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Evaluation of Clinical Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

The aim of this study is the characterization from epidemiological, radiomics and molecular point of view of lung metastasis of patients at beginning affected by pancreatic adenocarcinoma (PDAC), which after the resection of primitive tumor have met with initial recurrence of the disease exclusively at the lung level.

pancreatic adenocarcinoma
primary tumor
metastasis
pdac
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 4 locations
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

Post-authorization, observational, multicenter and prospective study in patients between 2 and 30 years old diagnosed with non-metastatic high-grade osteosarcoma of the extremities. All patients included in the study will receive the initial neoadjuvant treatment prescribed by the doctor of each center, according to standard practice (involving methotrexate, cisplatin, and adriamycin). …

ejection fraction
glycoprotein
adjuvant therapy
ifosfamide
localized disease
  • 0 views
  • 19 Feb, 2024
  • 17 locations