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Found 40 clinical trials
Tofacitinib for Immune Skin Conditions in Down Syndrome

People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions. The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug …

hidradenitis suppurativa
vitiligo
antibiotic
unbalanced translocation
eczema
  • 0 views
  • 19 Feb, 2024
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)

Interstitial lung diseases (ILD) are a highly incapacitating group of chronic respiratory diseases, leading to disabling symptoms and impaired capacity to perform activities of daily living and health-related quality of life (HRQoL). It is known that people with ILD are highly inactive and sedentary, and in a severe stage of …

  • 0 views
  • 19 Feb, 2024
Evaluation of Cognitive State Using Neurosteer EEG System

This is an observational study. Patients who fulfill all inclusion criteria and none of the exclusion criteria will be enrolled in the study, be neurologically evaluated and will go through EEG recordings while listening to an auditory cognitive assessment tool and preforming tasks. EEG recordings will be analyzed using proprietary …

mini-mental state examination
cognitive assessment
seizure
  • 0 views
  • 19 Feb, 2024
Integrative Therapy for Holistic Natural Cognition and Lifestyle Rehabilitation

An observational study to determine outcomes of older adults who are under naturopathic medical care for cognitive complaints at a specific clinic in Southern California.

cognitive assessment
  • 0 views
  • 19 Feb, 2024
Role of Nasal Dysbiosis in Parkinson Disease

We will search an association between microbiota and the presence of an olfactory deficit, cognitive deficit and thymic disorder.

parkinson's disease
deficit
motor symptoms
cognitive deficit
  • 0 views
  • 19 Feb, 2024
Quantifying Digital Behavior on Smart Phones - Data From Stroke Survivors

In this study, we want to continuously record the interaction of 50 stroke survivors with their smartphones during the first 3 months after discharge. The linkage of smart phone use to function and quality of life will be assessed with standardized outcome measures at defined time points.

recurrent strokes
  • 0 views
  • 19 Feb, 2024
Temporal Disorders in Left and Right Brain-Damaged Patients

Time is an important function that permeates our everyday activities but it has been so far significantly under-investigated in neurological patients. For instance, it is known that right brain damaged (RBD) patients with spatial attentional deficit (neglect) are impaired in both the ability to estimate the duration of an event …

  • 0 views
  • 19 Feb, 2024
  • 1 location
The A-LIST WMM Insights Series

The main purpose of the Study is to develop an understanding over time and through multiple research projects, including surveys, interviews, online focus groups, and other primary research methodologies (A-LIST Research Projects) on what matters most to individuals concerned about brain health and those with and/or affected by Alzheimer's disease …

alzheimer's disease
  • 0 views
  • 19 Feb, 2024
The A-LIST WMM Insights Series

The main purpose of the Study is to develop an understanding over time and through multiple research projects, including surveys, interviews, online focus groups, and other primary research methodologies (A-LIST Research Projects) on what matters most to individuals concerned about brain health and those with and/or affected by Alzheimer's disease …

alzheimer's disease
  • 0 views
  • 19 Feb, 2024
Management and Outcomes of Patients Admitted to Coronary Care Units Depending on Degree of Frailty and Comorbidities

The Clinical Frailty Scale (CFS) is a global clinical measure of biological age, mixing co-morbidity, disability and cognitive impairment. The investigators have previously reported the potential importance of frailty for short-term (1 month) and medium-term outcome (1 year) in a NSTEMI population.

infarct
myocardial infarction
cognitive impairment
old myocardial infarction
angiography
  • 0 views
  • 19 Feb, 2024