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Found 408 clinical trials
Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations (NEOASIS)

In this study, the efficacy of botensilimab and balstilimab in mismatch repair deficient (dMMR) and mismatch repair proficient (pMMR) tumors will be assessed.

  • 0 views
  • 02 Dec, 2024
  • 1 location
Study of DC-CIK Combined With Chemotherapy for Advanced Solid Tumor

Combinations of Dendritic cell-activated cytokine-induced killer cell (DC-CIK) With chemotherapy treatment may enhance the immune response and stop cancer cells from growing.

psychiatric disorder
platelet count
solid tumor
brain metastases
advanced malignant solid tumor
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of Venetoclax in Combination With Azacytidine in AML Patients Selected Using Ex Vivo Drug Sensitivity Screening

This study will characterize the usability of ex vivo drug sensitivity testing for patient selection for selecting the responsive patients for venetoclax therapy. The exploratory study will aim to find novel combinations for overcoming resistance as well as finding/validating biomarkers for both sensitivity and resistance.

renal function
remission
heart disease
azacitidine
mitoxantrone
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pelvic Floor Magnetic Stimulation in Women With Idiopathic Overactive Bladder

Moreover, there is no recommendation on conservative treament combinations in the guidelines due to insufficient data. At this stage, studies are needed to determine whether it will be effective to use MS in combination with other conservative treatment options.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

root canal
  • 0 views
  • 19 Feb, 2024
  • 1 location
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Background People with rare cancers often have limited treatment options. The biology of rare cancers is not well understood. Researchers want to find better treatments for these cancers. They want to test 2 drugs that, taken separately, have helped people with non-rare cancers. They want to see if these drugs …

desmoid tumors
vulvar cancer
adenocarcinoma
metastasis
nitrosoureas
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor Copanlisib Given in Combination With the Immunotherapeutic Agents Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

Patients with relapsed or refractory follicular or marginal zone lymphoma who have received at least one prior line of therapy will receive Copanlisib IV: day 1, 8, 15 every 28 days Nivolumab IV: Cycle 1 days 1 and 15; then day 1 only Rituximab IV: Cycle 1 days 1, 8, …

psychiatric disorder
cardiac arrhythmia
alcoholic cirrhosis
psoriasis
corticosteroids
  • 0 views
  • 19 Feb, 2024
  • 1 location
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

brain surgery
corticosteroids
cytotoxic chemotherapy
PCR test
nitrosoureas
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sentinel Lymph Node Biopsy With Hybrid Technique in Breast Cancer

Sentinel lymph node (SLN) biopsy is the gold standard method to stage axilla in breast cancer. The aim of the study is to compare the efficiency of various methods to identify SLN is breast cancer patients.

sentinel lymph node biopsy
sentinel node
excisional biopsy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Honey Products for Cancer Patients With Oral Mucositis: a Randomized Controlled Trial

The investigators plan to conduct a 3-year pioneering care research project for mucositis in cancer patients. These include: (1) an analysis of the incidence and severity of mucositis, severity, treatment methods, and treatment costs; (2) an RCT comparing the effectiveness of honey, Taiwan green propolis, and usual care in mucositis …

stomatitis
propolis
neck cancer
interleukin-6
head and neck cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location