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Found 2,831 clinical trials

D David G McMillan, DDS

Retention and Durability of the Anterior Zirconia Wing Bridge

This study is a clinical trial to determine the retention and durability of the anterior zirconia wing bridge. The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have three countersunk holes (meaning that the circumference of the outer portion of the hole …

18 years and older All Phase N/A
F Fabio Martinelli, MD

The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.

The role of small-volume lymph node disease (ITC and micro metastases) among patients with endometrial or cervical cancer submitted to sentinel node (SLN) procedure is not clearly defined. This study was designed to create a dataset of patients with lymph nodal disease. Data on type and volume of lymph nodal …

18 years and older Female Phase N/A
P Pauleen Sanchez, BA

Evaluating Cascade Communication Methods

Hereditary cancer programs face challenges with respect to effective communication of genetic test results within families and uptake of genetic testing by relatives. This study aims to determine if a "disclosure toolkit" provided to the index participant (carrier of cancer risk gene mutation) contributes to sharing genetic test results with …

18 years and older All Phase N/A
D Dawit Wolday, MD, PhD

Rapid Diagnostic Profiling of SARS-CoV-2 (COVID-19)

The investigators will evaluate the profile of the immune response of Ethiopian population and examine its relationship with the noted low CD4+ T-cell count and underlying immune activation status among participants with COVID-19 and will compare results with those residing in Europe. Hence, this project will evaluate the performance of …

100 years and younger All Phase N/A
D Deborah L O'Connor, PhD RD

Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1a

The Canadian Paediatric Society recommends breastfeeding during COVID-19 infection. Human milk is the best form of infant nutrition providing significant protection against many illnesses for term and preterm infants. The impact of a pandemic on breastfeeding is unknown. This study seeks to address this public health issue. Breastmilk will be …

100 years and younger All Phase N/A
S Shreejana Pokharel

Heart Failure Monitoring With Eko Electronic Stethoscopes

This proof-of-concept study will evaluate the feasibility of the Eko DUO to measure signals relevant to heart failure (HF) decompensation, as well as the feasibility to develop an algorithm to model hemodynamic filling pressures in HF patients under active decompensation in a cardiac intensive care unit (CICU) or coronary care …

18 years and older All Phase N/A
R Research Delivery Operations Manager

PHenotyping patiENts Admitted to Hospital With cOvid-19 Infection and idenTifYing Prognostic markErs

PHENOTYPE is an investigator-led, observational cohort study which aims to explore the long-term outcomes of patients with COVID-19 infection and to identify potential risk factors and biomarkers that can prognosticate disease severity and trajectory.

18 years and older All Phase N/A
T Thierry Berghmans, MD, PhD

Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

18 years and older All Phase N/A
C Christian Girbardt, MD

The Postoperative Head Position as a Predictor of the Surgical Outcome After DMEK

This study aims to investigate the influence of postoperative head position on clinical outcomes after DMEK via a wearable sensor.

18 years and older All Phase N/A
H Hong Liu, MD

Outcome of Patients Treated With ECLS

Extracorporeal life support (ECLS), also called extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique of providing effective circulatory and (or) respiratory failure, with a growing number of critically ill patients benefit from it. The aim of this study is to investigate the outcome of patients treated With ECMO, and to …

1 years and older All Phase N/A

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