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Found 275 clinical trials
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A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

karnofsky performance status
renal cell carcinoma
carcinoma
  • 0 views
  • 19 Feb, 2024
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic).

carcinoma
vasectomy
direct bilirubin
liver metastasis
anticoagulants
  • 8 views
  • 19 Feb, 2024
  • 1 location
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This may help doctors and patients with renal tumors in the future to make better treatment decisions.

renal neoplasm
MRI
hyperpolarized carbon c 13 pyruvate
cancer
aggressiveness
  • 0 views
  • 19 Feb, 2024
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

BRAF
lymphoma
advanced renal cell carcinoma
triple negative breast cancer
alopecia
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  • 19 Feb, 2024
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

recurrent disease
systemic corticosteroid therapy
trastuzumab
cytokine release syndrome
biotherapy
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  • 19 Feb, 2024