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Found 275 clinical trials
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A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

karnofsky performance status
carcinoma
renal cell carcinoma
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic).

azoospermia
chorionic gonadotropin
primary tumor
aptt
cancer
  • 8 views
  • 19 Feb, 2024
  • 1 location
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This may help doctors and patients with renal tumors in the future to make better treatment decisions.

estimated creatinine clearance
MRI
abdominal mri
hyperpolarized carbon c 13 pyruvate
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

pd-l1
gastric cancer
cancer
esophageal carcinoma
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

corticosteroid therapy
mibg
iobenguane
biological therapy
apheresis
  • 0 views
  • 19 Feb, 2024
  • 1 location